Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789051 | 1.00 | S100B (0.36) | S100BAPPESR2LTA4HESR1 | |
| SCHEMBL15037459 | 0.87 | TDP1 (0.39) | APPNOS3NOS2HTR3EHTR3B | |
| SCHEMBL15018842 | 0.85 | LTA4H (0.38) | ESR2LTA4HESR1NOS3NOS2 | |
| SCHEMBL15018839 | 0.85 | LTA4H (0.38) | ESR2LTA4HESR1NOS3NOS2 | |
| SCHEMBL16369055 | 0.84 | LTA4H (0.42) | ESR2LTA4HESR1NOS3NOS2 | |
| SCHEMBL15017930 | 0.83 | LTA4H (0.41) | LTA4HESR1MEN1LMNAMAPT | |
| SCHEMBL15017928 | 0.83 | LTA4H (0.41) | LTA4HESR1MEN1LMNAMAPT | |
| SCHEMBL11794810 | 0.83 | NOS3 (0.34) | ESR2NOS3NOS2CA1CA2 | |
| SCHEMBL11584573 | 0.82 | PABPC1 (0.42) | APPESR2ESR1CA2CA12 | |
| SCHEMBL15037462 | 0.81 | CYP19A1 (0.30) | APPMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9226883-B2 | Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof | L'OREAL (FR) | 2016-01-05 | — | — | US | disclosed |
| US-9226883-B2 | Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof | L'OREAL (FR) | 2016-01-05 | — | — | US | disclosed |
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | L'OREAL (FR) | 2015-01-01 | — | — | US | disclosed |
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | L'OREAL (FR) | 2015-01-01 | — | — | US | disclosed |
| WO-2013087636-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150000688-A1 | PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF | KRT18, IK, MKI67 | S100B 295/4885APP 834/4885ESR2 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.