Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102444 | 0.87 | ALDH1A1 (0.53) | NPSR1ALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL3378112 | 0.87 | ALDH1A1 (0.43) | NPSR1ALDH1A1HTTPRKACAROCK1 | |
| SCHEMBL13102109 | 0.85 | LMNA (0.43) | NPSR1ALDH1A1HTTPRKACAROCK1 | |
| SCHEMBL13102264 | 0.84 | ALDH1A1 (0.46) | NPSR1ALDH1A1HTTGLSMAPT | |
| SCHEMBL13102069 | 0.83 | NPSR1 (0.41) | NPSR1ALDH1A1HTTPRKACAROCK1 | |
| SCHEMBL13102314 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1MAPTSIGMAR1LMNAMEN1 | |
| SCHEMBL13101709 | 0.83 | MEN1 (0.44) | NPSR1ALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL13102241 | 0.83 | ALDH1A1 (0.44) | NPSR1ALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL3381133 | 0.82 | RAB9A (0.48) | NPSR1ALDH1A1HTTPRKACAROCK1 | |
| SCHEMBL13101669 | 0.82 | SIGMAR1 (0.42) | NPSR1ALDH1A1HTTPRKACAROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663237-B1 | FUSED RING HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN INC (US) | 2013-06-19 | — | — | EP | disclosed |