Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038529 | 0.83 | — | — | |
| SCHEMBL15038933 | 0.80 | P2RX7 (0.32) | RAB9APOLBALDH1A1GAAP2RX7 | |
| SCHEMBL10047661 | 0.75 | RAB9A (0.48) | RAB9ANPSR1POLBMEN1KMT2A | |
| SCHEMBL15215726 | 0.71 | SMN1; SMN2 (0.44) | RAB9ANPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10047675 | 0.68 | RAB9A (0.41) | RAB9ANPSR1POLBMEN1KMT2A | |
| SCHEMBL15038467 | 0.66 | RAB9A (0.37) | RAB9ANPSR1POLBMEN1KMT2A | |
| SCHEMBL15038462 | 0.62 | RAB9A (0.39) | RAB9ANPSR1POLBMEN1KMT2A | |
| SCHEMBL13131547 | 0.62 | NPSR1 (0.57) | NPSR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11625992 | 0.59 | BCL2 (0.58) | NPSR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15038511 | 0.59 | RAB9A (0.51) | RAB9AMEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604260-A1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Shionogi&Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |