SCHEMBL15038524

SCHEMBL15038524

c1ccc(-c2ccc(-c3cccc(N(c4cccc(-c5ccc(-c6ccccc6)cc5)c4)c4ccccc4-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
MEN1 O00255 1/20 0.39
APAF1 O14727 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
XBP1 P17861 1/20 0.39
PTBP1 P26599 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
SMAD3 P84022 1/20 0.39
KMT2A Q03164 1/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MGLL Q99685 1/20 0.37
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15038390 1.00 NPC1 (0.39) NPC1MEN1APAF1LMNAMAPT
SCHEMBL15038391 1.00 NPC1 (0.39) NPC1MEN1APAF1LMNAMAPT
SCHEMBL15038388 0.98 MGLL (0.38) NPC1MEN1APAF1LMNAMAPT
SCHEMBL15038387 0.96 MAPT (0.37) NPC1MEN1APAF1LMNAMAPT
SCHEMBL15038527 0.96 MGLL (0.37) NPC1MEN1APAF1LMNAMAPT
SCHEMBL15038399 0.96 MGLL (0.37) NPC1MEN1APAF1LMNAMAPT
SCHEMBL23437377 0.95 L3MBTL1 (0.37) NPC1MEN1APAF1LMNAMAPT
SCHEMBL19998698 0.95 ACMSD (0.37) NPC1MEN1APAF1LMNAMAPT
SCHEMBL21250648 0.95 ACMSD (0.37) NPC1MEN1APAF1LMNAMAPT
SCHEMBL15038386 0.95 ACMSD (0.37) NPC1MEN1APAF1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2826079-B1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-01-20 EP disclosed
US-10665787-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2020-05-26 US disclosed
EP-3230402-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-04-15 EP disclosed
US-10454040-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-10-22 US disclosed
US-10424739-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2019-09-24 US disclosed
US-10381576-B2 Electronic device having an amine containing layer processed from solution MERCK PATENT GMBH (DE) 2019-08-13 US disclosed
EP-3460864-A1 ELECTRONIC DEVICES Merck Patent GmbH (DE) 2019-03-27 EP disclosed
US-10193094-B2 Organic light-emitting device having delayed fluorescence MERCK PATENT GMBH (DE) 2019-01-29 US disclosed
US-10008672-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2018-06-26 US disclosed
US-10008672-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2018-06-26 US disclosed
US-20150340619-A1 Electronic Device MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150236261-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-08-20 US disclosed
US-20150236261-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-08-20 US disclosed
US-20150115239-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-30 US disclosed
US-20150115239-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-30 US disclosed
US-20140312287-A1 Compounds for Electronic Devices MERCK PATENT GMBH (DE) 2014-10-23 US disclosed
US-20140312287-A1 Compounds for Electronic Devices MERCK PATENT GMBH (DE) 2014-10-23 US disclosed
WO-2014106523-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-07-10 WO disclosed
WO-2014106521-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-07-10 WO disclosed
WO-2013087142-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10008672-B2 Compounds for electronic devices KCNQ2, DDT, KCNQ1 NPC1 637/4885MEN1 1791/4885APAF1 3844/4885
US-10424739-B2 Compounds for electronic devices KCNQ2, DDT, KCNQ1 NPC1 637/4885MEN1 1791/4885APAF1 3844/4885
US-10665787-B2 Compounds for electronic devices KCNQ2, DDT, KCNQ1 NPC1 637/4885MEN1 1791/4885APAF1 3844/4885
US-10381576-B2 Electronic device having an amine containing layer processed from solution OCIAD1, OCIAD2, AOC2 NPC1 1163/4885MEN1 611/4885APAF1 3605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.