Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703760 | 0.78 | CYP2A6 (0.46) | PGRCYP2A6ALDH1A1POLBCYP19A1 | |
| SCHEMBL21130940 | 0.78 | PGR (0.46) | PGRALDH1A1CA2 | |
| SCHEMBL10582903 | 0.78 | CYP2A6 (0.40) | PGRCYP2A6ALDH1A1LOXL2 | |
| SCHEMBL3619202 | 0.78 | PGR (0.58) | PGRCYP2A6ALDH1A1CA12CA2 | |
| SCHEMBL29790403 | 0.78 | PGR (0.50) | PGRCYP2A6ALDH1A1POLB | |
| SCHEMBL9553084 | 0.77 | PGR (0.40) | PGRCYP2A6ALDH1A1CYP19A1CA12 | |
| SCHEMBL18722099 | 0.77 | ALDH1A1 (0.43) | ALDH1A1POLBCA2 | |
| SCHEMBL16700954 | 0.76 | DGAT1 (0.43) | PGRCA12CA2CA3CA6 | |
| SCHEMBL7025606 | 0.75 | PGR (0.42) | PGRCYP2A6CYP19A1 | |
| SCHEMBL16700679 | 0.75 | PGR (0.47) | PGRALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |