Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193750 | 0.82 | ESR1 (0.42) | ESR1 | |
| SCHEMBL13392645 | 0.76 | ESR1 (0.39) | ESR1CYP19A1 | |
| SCHEMBL4188211 | 0.76 | ESR1 (0.39) | ESR1CYP19A1 | |
| SCHEMBL13392653 | 0.76 | ESR1 (0.39) | ESR1CYP19A1 | |
| SCHEMBL20110152 | 0.74 | ESR1 (0.38) | ESR1 | |
| SCHEMBL28771922 | 0.73 | ESR1 (0.35) | ESR1 | |
| SCHEMBL14570720 | 0.68 | G6PD (0.46) | — | |
| SCHEMBL13642578 | 0.68 | G6PD (0.46) | — | |
| SCHEMBL14598772 | 0.67 | ESR1 (0.43) | ESR1CYP19A1 | |
| SCHEMBL13642708 | 0.67 | G6PD (0.56) | ESR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9775903-B2 | 1-deoxy analogs of 1,25-dihydroxyvitamin D3 compounds | JOHNS HOPKINS UNIVERSITY (US) | 2017-10-03 | — | — | US | disclosed |
| US-20130157987-A1 | 1-DEOXY ANALOGS OF 1,25-DIHYDROXYVITAMIN D3 COMPOUNDS | JOHNS HOPKINS UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157987-A1 | 1-DEOXY ANALOGS OF 1,25-DIHYDROXYVITAMIN D3 COMPOUNDS | CYP24A1, CYP2R1, CYP27B1 | ESR1 871/4885CYP19A1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.