SCHEMBL9820115

SCHEMBL9820115

Cc1ccc(S(=O)(=O)c2ccc(C)cc2CCCl)c(CCCl)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.36
GAA P10253 1/20 0.34
AMY1A P0DUB6 1/20 0.34
ALDH1A1 P00352 4/20 0.34
MAPT P10636 4/20 0.34
POLB P06746 3/20 0.34
NQO1 P15559 3/20 0.33
POR P16435 3/20 0.33
KMT2A Q03164 1/20 0.33
MEP1B Q16820 1/20 0.33
PTGES2 Q9H7Z7 3/20 0.33
GPR55 Q9Y2T6 2/20 0.33
RAPGEF4 Q8WZA2 2/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
THRB P10828 1/20 0.32
UBE2N P61088 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1504600 0.86 PTGES2 (0.42) TAAR1AMY1AALDH1A1MAPTPOLB
SCHEMBL755113 0.86 GAA (0.37) TAAR1GAAAMY1AALDH1A1MAPT
SCHEMBL30239066 0.86 PTGES2 (0.42) TAAR1AMY1AALDH1A1MAPTPOLB
SCHEMBL8079008 0.85 KMT2A (0.40) TAAR1GAAAMY1AALDH1A1MAPT
SCHEMBL4138945 0.80 RAPGEF4 (0.42) TAAR1GAAAMY1AALDH1A1MAPT
SCHEMBL5957559 0.79 CNR2 (0.40) GAAALDH1A1MAPTKMT2APTGES2
SCHEMBL5757189 0.78 PSEN1 (0.39) KMT2APTGES2
SCHEMBL9820124 0.78 CNR2 (0.39) GAAMAPTKMT2AHTTTDP1
SCHEMBL10686098 0.77 ALDH1A1 (0.39) GAAALDH1A1MAPTKMT2AHTT
SCHEMBL11680272 0.77 MEP1B (0.38) TAAR1GAAAMY1AALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182299-B1 A CURABLE FLUOROELASTOMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-04-03 EP disclosed
US-4748208-A FLUOROPOLYMER, BIS/PHOSPHINE/IMINIUM HALIDE, POLYHYDROXY CURING AGENT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-05-31 US disclosed
EP-0182299-A2 A curable fluoroelastomer composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-05-28 EP disclosed