Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | F9 | P00740 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438413 | 0.81 | MAPT (0.48) | MAPTPKMALDH1A1RAB9ANPC1 | |
| SCHEMBL16489816 | 0.78 | TAS1R3 (0.64) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL4494177 | 0.77 | JAK1 (0.50) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL7890595 | 0.75 | CTSB (0.47) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL13282255 | 0.75 | CTSB (0.47) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL4489378 | 0.75 | CTSB (0.47) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL28854927 | 0.75 | CPB1 (0.64) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL8296191 | 0.75 | CPB1 (0.64) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL8297367 | 0.74 | TAS1R3 (0.62) | TAS1R3TAS1R1F9F10PRSS1 | |
| SCHEMBL14534581 | 0.73 | TAS1R3 (0.48) | TAS1R3TAS1R1F9F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090929-A1 | AMINO QUINOLINE DERIVATIVES INHIBITORS OF HCV | GILEAD SCIENCES, INC. (US) | 2013-06-20 | — | — | WO | disclosed |