Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623050 | 0.90 | ALDH1A1 (0.45) | MAPTTSHRPPARGALDH1A1POLB | |
| SCHEMBL3954380 | 0.90 | ALDH1A1 (0.45) | MAPTTSHRPPARGALDH1A1POLB | |
| SCHEMBL15047164 | 0.88 | HTR2B (0.47) | HTR2BCYP3A4HPGDMAPTTSHR | |
| SCHEMBL21515743 | 0.85 | HTR2B (0.38) | HTR2BMAPTTSHRTDP1KDM4E | |
| SCHEMBL21515741 | 0.85 | HTR2B (0.38) | HTR2BMAPTTSHRTDP1KDM4E | |
| SCHEMBL3330847 | 0.84 | HTR2B (0.48) | HTR2BCYP3A4HPGDMAPTALDH1A1 | |
| SCHEMBL13298925 | 0.84 | HTR2B (0.48) | HTR2BCYP3A4HPGDMAPTALDH1A1 | |
| SCHEMBL14028912 | 0.84 | HTR2B (0.48) | HTR2BCYP3A4HPGDALDH1A1KMT2A | |
| SCHEMBL5622788 | 0.83 | MAPT (0.49) | HPGDMAPTTSHRALDH1A1POLB | |
| SCHEMBL15047712 | 0.78 | HTR2B (0.43) | HTR2BHPGDMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220105078-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-04-07 | — | — | US | disclosed |
| US-20170209420-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-07-27 | — | — | US | disclosed |
| US-20140343110-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-11-20 | — | — | US | disclosed |
| WO-2013090750-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220105078-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | TFRC, AIFM2, VIP | HTR2B 695/4885CYP3A4 3371/4885HPGD 1039/4885 |
| US-20140343110-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | TFRC, AIFM2, VIP | HTR2B 672/4885CYP3A4 3327/4885HPGD 972/4885 |
| US-20170209420-A1 | USES OF 4'-DESFERRITHIOCIN ANALOGS | TFRC, AIFM2, VIP | HTR2B 672/4885CYP3A4 3327/4885HPGD 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.