Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555938 | 0.91 | CES2 (0.65) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL28959084 | 0.90 | MAPT (0.61) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL9117609 | 0.86 | LMNA (0.63) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL13273458 | 0.86 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL79445 | 0.85 | HDAC2 (0.64) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL29779494 | 0.84 | SMN1; SMN2 (0.65) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL28959072 | 0.84 | CES2 (0.60) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| Chlorobenzene SCHEMBL28816973 | 0.83 | NPC1 (0.61) | MAPTALDH1A1L3MBTL1PTGS2CES2 | |
| SCHEMBL24554797 | 0.83 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL14486438 | 0.83 | LMNA (0.59) | MAPTALDH1A1KDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158063-A1 | Compounds, Compositions and Methods Related to PPAR Antagonists | GEORGETOWN UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158063-A1 | Compounds, Compositions and Methods Related to PPAR Antagonists | PPARG, PPARA, PPARD | MAPT 4631/4885ALDH1A1 1567/4885KDM4E 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.