Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751992 | 0.89 | L3MBTL1 (0.55) | ALDH1A1KDM4ETSHRPTGER1PTGER4 | |
| SCHEMBL8163440 | 0.88 | TSHR (0.54) | ALDH1A1KDM4ETSHRPTGER1PTGER4 | |
| SCHEMBL8158272 | 0.88 | TSHR (0.54) | ALDH1A1KDM4ETSHRPTGER1PTGER4 | |
| SCHEMBL9501831 | 0.83 | POLB (0.56) | KDM4ETSHRPTGER1PTGER4PTGER3 | |
| SCHEMBL7695345 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4ETSHRPTGER1PTGER4 | |
| SCHEMBL28759656 | 0.83 | L3MBTL1 (0.48) | ALDH1A1KDM4ETSHRPTGER1PTGER4 | |
| SCHEMBL3043854 | 0.81 | TSHR (0.61) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL8158403 | 0.80 | HDAC3 (0.52) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL22782667 | 0.79 | TSHR (0.59) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL8355272 | 0.79 | TSHR (0.59) | ALDH1A1TSHRKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470861-B2 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER (US) | 2013-06-25 | — | — | US | claimed |