Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048558 | 0.89 | ALDH1A1 (0.51) | L3MBTL1LMNAKMT2AMEN1PTGER1 | |
| SCHEMBL18467924 | 0.88 | L3MBTL1 (0.47) | L3MBTL1LMNAKMT2AMEN1MCL1 | |
| SCHEMBL7379938 | 0.83 | SCN4A (0.46) | L3MBTL1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3726341 | 0.81 | KMT2A (0.44) | L3MBTL1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3723813 | 0.80 | PPARG (0.66) | L3MBTL1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL830740 | 0.80 | KMT2A (0.60) | L3MBTL1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9501831 | 0.80 | POLB (0.56) | L3MBTL1KMT2AMCL1PTGER1PTGER4 | |
| SCHEMBL7695345 | 0.80 | KDM4E (0.55) | L3MBTL1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3046950 | 0.79 | LMNA (0.69) | L3MBTL1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL21595893 | 0.78 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053918-B1 | PROPYL PHENOXY ETHERS FOR USE AS DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2014-07-23 | — | — | EP | disclosed |
| EP-2053918-B1 | PROPYL PHENOXY ETHERS FOR USE AS DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-7968736-B2 | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof | University of Pittsburgh—of the Commonwelth Systems of Higher Education (US) | 2011-06-28 | — | — | US | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EMISPHERE TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | US | disclosed |
| US-20090036691-A1 | ANALOGS OF DICODERMOLIDE AND DICTYOSTATIN-1, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF | PITTSBURGH UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER | 2009-02-05 | — | — | US | disclosed |
| US-20060270862-A1 | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof | PITTSBURGH, UNIVERSITY OF | 2006-11-30 | — | — | US | disclosed |
| US-7122686-B2 | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof | UNIVERSITY OF PITTSBURGH (US) | 2006-10-17 | — | — | US | disclosed |
| US-20040186165-A1 | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-09-23 | — | — | US | disclosed |
| WO-2004022552-A1 | ANALOGS OF DISCODERMOLIDE AND DICTYOSTATIN-1, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF | UNIVERSITY OF PITTSBURGH (US) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062970-A1 | SYNTHESIS OF PROPYL PHENOXY ETHERS AND USE AS DELIVERY AGENTS | EPX, HPD, CYP2C8 | L3MBTL1 3481/4885LMNA 2327/4885KMT2A 2202/4885 |
| US-20090036691-A1 | ANALOGS OF DICODERMOLIDE AND DICTYOSTATIN-1, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF | RRS1, RPS3A, RPS3 | L3MBTL1 689/4885LMNA 3098/4885KMT2A 2627/4885 |
| US-20060270862-A1 | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof | RRS1, RPS6KA3, RPS6KA4 | L3MBTL1 766/4885LMNA 1958/4885KMT2A 3918/4885 |
| US-20040186165-A1 | Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof | DECR1, RRS1, WEE1 | L3MBTL1 146/4885LMNA 597/4885KMT2A 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.