SCHEMBL15048642

SCHEMBL15048642

C=CCc1ccc(OC(=O)CC(C(=O)Oc2ccc(CC=C)cc2)S(=O)(=O)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
THRB P10828 2/20 0.35
MMP2 P08253 1/20 0.35
PTGS1 P23219 1/20 0.35
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 4/20 0.33
PRSS1 P07477 1/20 0.32
TMPRSS15 P98073 1/20 0.32
MEN1 O00255 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1592207 0.78 ATM (0.41) SMN1; SMN2ALDH1A1ALOX15HSD17B10CYP1A2
SCHEMBL29082640 0.77 KMT2A (0.49) SMN1; SMN2ALDH1A1HSD17B10KMT2AMEN1
SCHEMBL29082255 0.77 KMT2A (0.49) SMN1; SMN2ALDH1A1HSD17B10KMT2AMEN1
SCHEMBL7972963 0.77 ATM (0.41) SMN1; SMN2ALDH1A1ALOX15HSD17B10CYP1A2
SCHEMBL11362243 0.76 KMT2A (0.53) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL15048640 0.75 ADRB2 (0.41) ALDH1A1TSHRCYP1A2CYP2D6KMT2A
SCHEMBL1777270 0.75 CASP1 (0.41) SMN1; SMN2CYP3A4ALDH1A1TSHRTHRB
SCHEMBL3420088 0.75 ALDH1A1 (0.52) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL28036279 0.74 THRB (0.51) CYP3A4ALDH1A1TP53THRBPTGS1
SCHEMBL10192354 0.73 SMN1; SMN2 (0.55) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470741-B2 oil-based concentrate which is homogenous for at least 24 hours and which emulsifies readily on dilution into water CRODA AMERICAS LLC (US) 2013-06-25 US claimed