Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498875 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL28961749 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL29991778 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL15048681 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL498876 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL1141446 | 0.98 | PTPN1 (0.54) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL1141447 | 0.98 | PTPN1 (0.54) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL21645848 | 0.89 | ACHE (0.48) | PTPN1EP300ACHEBACE1PPARG | |
| SCHEMBL31203472 | 0.89 | ACHE (0.48) | PTPN1EP300ACHEBACE1PPARG | |
| SCHEMBL29706604 | 0.89 | ACHE (0.48) | PTPN1EP300ACHEBACE1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11230704-B2 | Oxidation of highly unsaturated fatty acids with novel 8-lipoxygenase derived from Malacostraca | BIZEN CHEMICAL CO., LTD. (JP) | 2022-01-25 | — | — | US | claimed |
| US-20210115411-A1 | NOVEL 8-LIPOXYGENASE AND USE THEREOF | IWATE PREFECTURAL GOVERNMENT (JP) | 2021-04-22 | — | — | US | claimed |
| US-20130274327-A1 | NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID | THE UNIVERSITY OF TOKYO (JP) | 2013-10-17 | — | — | US | claimed |
| EP-2607358-A1 | NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID | The University of Tokyo (JP) | 2013-06-26 | — | — | EP | claimed |
| US-11230704-B2 | Oxidation of highly unsaturated fatty acids with novel 8-lipoxygenase derived from Malacostraca | BIZEN CHEMICAL CO., LTD. (JP) | 2022-01-25 | — | — | US | disclosed |
| US-20210115411-A1 | NOVEL 8-LIPOXYGENASE AND USE THEREOF | IWATE PREFECTURAL GOVERNMENT (JP) | 2021-04-22 | — | — | US | disclosed |
| US-9238634-B2 | Anti-inflammatory metabolite derived from omega-3-type fatty acid | THE UNIVERSITY OF TOKYO (JP) | 2016-01-19 | — | — | US | disclosed |
| US-20130274327-A1 | NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID | THE UNIVERSITY OF TOKYO (JP) | 2013-10-17 | — | — | US | disclosed |
| EP-2607358-A1 | NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID | The University of Tokyo (JP) | 2013-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274327-A1 | NOVEL ANTI-INFLAMMATORY METABOLITE DERIVED FROM OMEGA-3-TYPE FATTY ACID | PTGES3, ALOX5, ALOX15 | PTPN1 1775/4885EP300 2195/4885ACHE 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.