Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048680 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL498875 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL28961749 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL29991778 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL15048681 | 1.00 | PTPN1 (0.53) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL1141446 | 0.98 | PTPN1 (0.54) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL1141447 | 0.98 | PTPN1 (0.54) | PTPN1EP300ACHEBACE1KDM4E | |
| SCHEMBL21645848 | 0.89 | ACHE (0.48) | PTPN1EP300ACHEBACE1PPARG | |
| SCHEMBL31203472 | 0.89 | ACHE (0.48) | PTPN1EP300ACHEBACE1PPARG | |
| SCHEMBL29706604 | 0.89 | ACHE (0.48) | PTPN1EP300ACHEBACE1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240173285-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-05-30 | — | — | US | claimed |
| EP-4329742-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | Amarin Pharmaceuticals Ireland Limited (IE) | 2024-03-06 | — | — | EP | claimed |
| US-20230284643-A1 | MILK PRODUCT COMPOSITIONS | BIOMILQ INC (US) | 2023-09-14 | — | — | US | claimed |
| EP-4157990-A1 | MILK PRODUCT COMPOSITIONS | Biomilq, Inc. (US) | 2023-04-05 | — | — | EP | claimed |
| US-20230043035-A1 | AGAROPHYTON CHILENSIS EXTRACT, RICH IN FREE FATTY ACIDS, AS A NUTRACEUTICAL OR NUTRITIONAL SUPPLEMENT, SUITABLE FOR MODULATING PPAR# ACTIVITY | UNIVERSIDAD ANDRES BELLO (CL) | 2023-02-09 | — | — | US | claimed |
| CN-115698252-A | Dairy product composition | 生物乳业公司 | 2023-02-03 | — | — | CN | claimed |
| WO-2022232633-A1 | COMPOSITIONS COMPRISING EPA AND METHODS OF USING THE SAME FOR TREATING AND/OR PREVENTING ENDOTHELIAL DYSFUNCTION IN A SUBJECT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2022-11-03 | — | — | WO | claimed |
| WO-2022198812-A1 | SEROLOGICAL MARKER FOR ASSESSING ALLERGEN-SPECIFIC IMMUNOTHERAPY EFFECT | 广州医科大学附属第一医院（广州呼吸中心） | 2022-09-29 | — | — | WO | claimed |
| WO-2022198813-A1 | USE OF 15(S)-HYDROXYEICOSATETRAENOIC ACID IN EVALUATION OF EFFECT OF ALLERGEN SPECIFIC IMMUNOTHERAPY | 广州医科大学附属第一医院（广州呼吸中心） | 2022-09-29 | — | — | WO | claimed |
| US-11230704-B2 | Oxidation of highly unsaturated fatty acids with novel 8-lipoxygenase derived from Malacostraca | BIZEN CHEMICAL CO., LTD. (JP) | 2022-01-25 | — | — | US | claimed |
| WO-2021242866-A1 | MILK PRODUCT COMPOSITIONS | BIOMILQ, Inc. (US) | 2021-12-02 | — | — | WO | claimed |
| CN-113155996-A | Use of 15(S) -hydroxyeicosatetraenoic acid for evaluating allergen specific immunotherapy efficacy | 广州医科大学附属第一医院（广州呼吸中心） | 2021-07-23 | — | — | CN | claimed |
| CN-113049802-A | Serological marker for evaluating allergen-specific immunotherapy effect | 广州医科大学附属第一医院（广州呼吸中心） | 2021-06-29 | — | — | CN | claimed |
| US-20210115411-A1 | NOVEL 8-LIPOXYGENASE AND USE THEREOF | IWATE PREFECTURAL GOVERNMENT (JP) | 2021-04-22 | — | — | US | claimed |
| WO-2014015318-A1 | SOLUBLE COMPOUNDS FOR IMPROVED GENE THERAPY METHODS | BLUEBIRD BIO, INC. (US) | 2014-01-23 | — | — | WO | claimed |
| US-20130316989-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE | RESOLVYX PHARMACEUTICALS, INC. (US) | 2013-11-28 | — | — | US | claimed |
| US-20110190242-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE | RESOLVYX PHARMACEUTICALS, INC. (US) | 2011-08-04 | — | — | US | claimed |
| EP-1566202-A1 | Use of resistin antagonists in the treatment of rheumatoid arthritis | Sahltech I Göteborg AB (SE) | 2005-08-24 | — | — | EP | claimed |
| WO-2003084532-A1 | LIPOIC ACID ANALOGS USEFUL AS PROVITAMINS AND ANTIOXIDANTS | AVERY MITCHELL A (US) | 2003-10-16 | — | — | WO | claimed |
| US-20020048798-A1 | Novel antioxidants | AVERY MITCHELL ALLEN (US) | 2002-04-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130316989-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE | ALOX15B, ALOX12, ALOX15 | PTPN1 3245/4885EP300 2066/4885ACHE 3371/4885 |
| US-20110190242-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATORY DISEASE | ALOX15B, ALOX12, ALOX15 | PTPN1 3245/4885EP300 2066/4885ACHE 3371/4885 |
| US-20020048798-A1 | Novel antioxidants | CUTA, LIPG, NFATC1 | PTPN1 1402/4885EP300 2301/4885ACHE 1167/4885 |
| US-20230043035-A1 | AGAROPHYTON CHILENSIS EXTRACT, RICH IN FREE FATTY ACIDS, AS A NUTRACEUTICAL OR NUTRITIONAL SUPPLEMENT, SUITABLE FOR MODULATING PPAR# ACTIVITY | PPARG, FFAR1, PPARA | PTPN1 2757/4885EP300 686/4885ACHE 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.