Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 10/20 | 0.77 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15061860 | 0.93 | LPAR1 (0.68) | LPAR1LPAR3SMN1; SMN2ENPP2MGLL | |
| SCHEMBL30299188 | 0.87 | LPAR1 (1.00) | LPAR1LPAR3SMN1; SMN2ENPP2MGLL | |
| Glycerol Phenylbutyrate SCHEMBL10102804 | 0.82 | ADRB2 (0.56) | LPAR1SMN1; SMN2MGLLHDAC3HDAC4 | |
| SCHEMBL15048820 | 0.79 | MGLL (0.74) | LPAR1SMN1; SMN2MGLLHDAC3HDAC4 | |
| SCHEMBL15049869 | 0.78 | LPAR1 (0.51) | LPAR1LPAR3SMN1; SMN2ENPP2 | |
| SCHEMBL15048732 | 0.78 | LPAR1 (0.62) | LPAR1SMN1; SMN2MGLLHDAC3HDAC4 | |
| SCHEMBL7780729 | 0.77 | HDAC1 (0.56) | LPAR1SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL1892709 | 0.77 | ALDH1A1 (0.56) | LPAR1MGLLFAAH | |
| SCHEMBL3784212 | 0.77 | ALDH1A1 (0.56) | LPAR1MGLLFAAH | |
| SCHEMBL15061844 | 0.76 | MGLL (0.61) | LPAR1SMN1; SMN2MGLLHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607366-A1 | Glycerol phenyl butyrate esters | Lunamed AG (CH) | 2013-06-26 | — | — | EP | disclosed |
| EP-2607366-A1 | Glycerol phenyl butyrate esters | Lunamed AG (CH) | 2013-06-26 | — | — | EP | disclosed |