Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12470503 | 0.90 | ALDH1A1 (0.66) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| SCHEMBL29434803 | 0.90 | ALDH1A1 (0.66) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL29194251 | 0.89 | ALDH1A1 (0.64) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| Crotonic Acid SCHEMBL28053102 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| Acrylic Acid SCHEMBL1505076 | 0.83 | ALDH1A1 (0.58) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| SCHEMBL10144027 | 0.82 | ALDH1A1 (0.74) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| SCHEMBL29020526 | 0.81 | MDM4 (0.67) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| Propanol SCHEMBL28052966 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2AHPGDMEN1CYP2C9 | |
| SCHEMBL6067716 | 0.81 | HDAC1 (0.66) | KMT2AHPGDMEN1CYP2C9ABCG2 | |
| SCHEMBL11600676 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KMT2AHPGDMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480523-B1 | PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2017-03-01 | — | — | EP | disclosed |
| US-20160115118-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2016-04-28 | — | — | US | disclosed |
| US-9242927-B2 | Process for the manufacture of N-acylbiphenyl alanine | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2016-01-26 | — | — | US | disclosed |
| US-20140142320-A1 | Process for the Manufacture of N-acylbiphenyl alanine | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20130172572-A1 | Process for Manufacture of N-acylbiphenyl alanine | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2013-07-04 | — | — | US | disclosed |
| EP-2480523-A1 | PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2012-08-01 | — | — | EP | disclosed |
| WO-2011035569-A1 | PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2011-03-31 | — | — | WO | disclosed |
| WO-2010034236-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115118-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ANPEP, DNPEP, ENPEP | ALDH1A1 1633/4885KMT2A 2804/4885HPGD 1134/4885 |
| US-20140142320-A1 | Process for the Manufacture of N-acylbiphenyl alanine | ANPEP, DNPEP, ENPEP | ALDH1A1 1633/4885KMT2A 2804/4885HPGD 1134/4885 |
| US-20130172572-A1 | Process for Manufacture of N-acylbiphenyl alanine | ANPEP, DNPEP, RNPEP | ALDH1A1 1757/4885KMT2A 2509/4885HPGD 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.