Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99181 | 0.90 | ALDH1A1 (0.59) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| Acrylic Acid SCHEMBL1505000 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| Propanol SCHEMBL28418591 | 0.82 | SOAT1 (0.60) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL11600676 | 0.81 | ALDH1A1 (0.68) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL9762630 | 0.79 | ALDH1A1 (0.57) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL29035926 | 0.79 | MEN1 (0.56) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL3640507 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL6326388 | 0.78 | ALDH1A1 (0.65) | ALDH1A1CYP2C9HPGDMAPTCYP1A2 | |
| SCHEMBL21522574 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL5213661 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2C9HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480523-B1 | PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE | ZHEJIANG JIUZHOU PHARM CO LTD (CN) | 2017-03-01 | — | — | EP | disclosed |
| US-20160115118-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2016-04-28 | — | — | US | disclosed |
| US-9242927-B2 | Process for the manufacture of N-acylbiphenyl alanine | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2016-01-26 | — | — | US | disclosed |
| US-20140142320-A1 | Process for the Manufacture of N-acylbiphenyl alanine | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20130172572-A1 | Process for Manufacture of N-acylbiphenyl alanine | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2013-07-04 | — | — | US | disclosed |
| EP-2480523-A1 | PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE | Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) | 2012-08-01 | — | — | EP | disclosed |
| WO-2011035569-A1 | PROCESS FOR MANUFACTURE OF N-ACYLBPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2011-03-31 | — | — | WO | disclosed |
| WO-2010034236-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115118-A1 | PROCESS FOR THE MANUFACTURE OF N-ACYLBIPHENYL ALANINE | ANPEP, DNPEP, ENPEP | ALDH1A1 1633/4885CYP2C9 667/4885HPGD 1134/4885 |
| US-20140142320-A1 | Process for the Manufacture of N-acylbiphenyl alanine | ANPEP, DNPEP, ENPEP | ALDH1A1 1633/4885CYP2C9 667/4885HPGD 1134/4885 |
| US-20130172572-A1 | Process for Manufacture of N-acylbiphenyl alanine | ANPEP, DNPEP, RNPEP | ALDH1A1 1757/4885CYP2C9 875/4885HPGD 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.