Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751294 | 0.78 | CDC7 (0.49) | CDC7RAB9ADHODH | |
| SCHEMBL27374955 | 0.78 | CDC7 (0.49) | CDC7RAB9ADHODH | |
| SCHEMBL2904460 | 0.77 | MERTK (0.54) | VCAM1MEN1KMT2AALOX12ABCG2 | |
| SCHEMBL15054549 | 0.77 | KIF11 (0.64) | VCAM1MEN1KMT2AABCG2KIF11 | |
| SCHEMBL2303201 | 0.76 | VCAM1 (0.74) | VCAM1MEN1KMT2AALDH1A1 | |
| SCHEMBL29664185 | 0.76 | ALOX12 (0.68) | MEN1KMT2AALOX12HPGDL3MBTL1 | |
| SCHEMBL30234162 | 0.74 | KIF11 (0.57) | MEN1KMT2AALOX12ABCG2HPGD | |
| SCHEMBL6757945 | 0.74 | VCAM1 (0.65) | VCAM1MEN1KMT2AABCG2MERTK | |
| SCHEMBL26310363 | 0.74 | KIF11 (0.57) | MEN1KMT2AALOX12ABCG2HPGD | |
| SCHEMBL7090977 | 0.74 | VCAM1 (0.91) | VCAM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096153-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |