Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | ARNT | P27540 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841678 | 0.87 | KIF11 (0.78) | KIF11MPOMEN1LMNAMAPT | |
| SCHEMBL16208490 | 0.83 | KIF11 (0.81) | KIF11MPOMEN1LMNAMAPT | |
| SCHEMBL27374858 | 0.79 | TDO2 (0.49) | KIF11MPOMAPTTAS2R14TDO2 | |
| SCHEMBL30751439 | 0.79 | TDO2 (0.49) | KIF11MPOMAPTTAS2R14TDO2 | |
| SCHEMBL7043192 | 0.79 | KIF11 (1.00) | KIF11MPOMEN1LMNAMAPT | |
| SCHEMBL23554076 | 0.79 | MAPT (0.61) | KIF11MEN1LMNAMAPTKMT2A | |
| SCHEMBL15054166 | 0.77 | VCAM1 (0.56) | KIF11MEN1LMNAMAPTKMT2A | |
| SCHEMBL16481386 | 0.76 | AKR1C3 (0.54) | KIF11MAPTTAS2R14TDO2RXFP1 | |
| SCHEMBL11145707 | 0.76 | KIF11 (0.68) | KIF11MPOMEN1LMNAMAPT | |
| SCHEMBL2480998 | 0.75 | VCAM1 (0.67) | KIF11VCAM1TAS2R14RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096153-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |