Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428597 | 1.00 | HTT (0.41) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| Hydrochloric Acid SCHEMBL7311086 | 0.98 | HTT (0.40) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| Hydrochloric Acid SCHEMBL15054835 | 0.98 | HTT (0.40) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| Hydrochloric Acid SCHEMBL9469017 | 0.95 | HTT (0.37) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| SCHEMBL14902206 | 0.80 | L3MBTL1 (0.42) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| SCHEMBL7646012 | 0.78 | CA12 (0.45) | HTTLIPEKDM4E | |
| SCHEMBL915516 | 0.77 | L3MBTL1 (0.40) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| SCHEMBL3875288 | 0.77 | HTT (0.41) | HTTL3MBTL1MAPTALDH1A1LIPE | |
| SCHEMBL4591725 | 0.77 | HTT (0.47) | HTTL3MBTL1MAPTALDH1A1POLB | |
| SCHEMBL1507938 | 0.77 | ALDH1A1 (0.43) | HTTL3MBTL1MAPTALDH1A1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093931-A2 | NOVEL PRODRUGS OF PHENOLIC DRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013093931-A2 | NOVEL PRODRUGS OF PHENOLIC DRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2013-06-27 | — | — | WO | disclosed |