Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997271 | 0.79 | GNAI3 (0.42) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL10703372 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTLIPE | |
| SCHEMBL1428597 | 0.77 | HTT (0.41) | ALDH1A1MAPTLMNAHTTLIPE | |
| SCHEMBL15054837 | 0.77 | HTT (0.41) | ALDH1A1MAPTLMNAHTTLIPE | |
| SCHEMBL3875288 | 0.77 | HTT (0.41) | ALDH1A1MAPTLMNAHTTLIPE | |
| SCHEMBL4591725 | 0.77 | HTT (0.47) | ALDH1A1MAPTSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL8725 | 0.76 | HTT (0.39) | ALDH1A1MAPTLMNAHTTLIPE | |
| SCHEMBL14902206 | 0.76 | L3MBTL1 (0.42) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL7311086 | 0.76 | HTT (0.40) | ALDH1A1MAPTLMNAHTTLIPE | |
| SCHEMBL9043266 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2POLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101921247-B | 1-(cinnamoyl)-4-piperidyl amide piperazidine compound and preparation method thereof | FUZHOU LUJIA MEDICAL TECHNOLOGY CO.,LTD. (CN) | 2016-04-20 | — | — | CN | claimed |
| CN-101921247-A | 1-(cinnamoyl)-4-piperidyl amide piperazidine compound and preparation method thereof | KAISHU XIE | 2010-12-22 | — | — | CN | claimed |
| CN-101921247-B | 1-(cinnamoyl)-4-piperidyl amide piperazidine compound and preparation method thereof | FUZHOU LUJIA MEDICAL TECHNOLOGY CO.,LTD. (CN) | 2016-04-20 | — | — | CN | disclosed |
| EP-2292595-A1 | Potassium channel modulators | NeuroSearch AS (DK) | 2011-03-09 | — | — | EP | disclosed |
| CN-101921247-A | 1-(cinnamoyl)-4-piperidyl amide piperazidine compound and preparation method thereof | KAISHU XIE | 2010-12-22 | — | — | CN | disclosed |
| US-7429618-B2 | Potassium channel modulators | NEUROSEARCH A/S (DK) | 2008-09-30 | — | — | US | disclosed |
| EP-1911740-A1 | POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2008-04-16 | — | — | EP | disclosed |
| US-20070161607-A1 | Potassium channel modulators | SANIONA A/S (DK) | 2007-07-12 | — | — | US | disclosed |
| US-7208527-B2 | Potassium channel modulators | POSEIDON PHARMACEUTICALS A/S (DK) | 2007-04-24 | — | — | US | disclosed |
| US-20050009816-A1 | Potassium channel modulators | SANIONA A/S (DK) | 2005-01-13 | — | — | US | disclosed |
| EP-1465863-A1 | POTASSIUM CHANNEL MODULATORS | Poseidon Pharmaceuticals A/S (DK) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059873-A1 | POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009816-A1 | Potassium channel modulators | KCNC1, KCNQ1, KCNA1 | ALDH1A1 3877/4885MAPT 2348/4885LMNA 2815/4885 |
| US-20070161607-A1 | Potassium channel modulators | KCNC1, KCNQ1, KCNA1 | ALDH1A1 3877/4885MAPT 2348/4885LMNA 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.