Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054540 | 0.84 | LMNA (0.44) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL1992837 | 0.73 | ALDH1A1 (0.45) | KDM4ERAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL28567653 | 0.70 | LMNA (0.45) | KDM4ERAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL2328573 | 0.68 | KDM4E (0.53) | KDM4ERAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL912444 | 0.68 | CHEK2 (0.59) | KDM4ERAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL9126131 | 0.68 | RAB9A (0.57) | KDM4ERAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL26107446 | 0.68 | KMT2A (0.41) | KDM4EALDH1A1KMT2AHPGDTSHR | |
| SCHEMBL31347284 | 0.68 | KMT2A (0.41) | KDM4EALDH1A1KMT2AHPGDTSHR | |
| SCHEMBL4982524 | 0.68 | TSHR (0.46) | KDM4ERAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8318161 | 0.67 | ALDH1A1 (0.50) | KDM4ERAB9ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |