Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252900 | 0.81 | TSHR (0.62) | TSHRP2RY12SMN1; SMN2PDK1PDK2 | |
| SCHEMBL7399909 | 0.79 | TSHR (0.50) | TSHRP2RY12SMN1; SMN2PDK1PDK2 | |
| SCHEMBL1314242 | 0.76 | PDK1 (0.45) | TSHRRAB9AP2RY12KITJAK2 | |
| SCHEMBL17560328 | 0.75 | PDK1 (0.41) | TSHRP2RY12PDK1PDK2PDK3 | |
| SCHEMBL15055247 | 0.75 | TSHR (0.53) | TSHRSMN1; SMN2 | |
| SCHEMBL15055244 | 0.75 | TSHR (0.53) | TSHRSMN1; SMN2 | |
| SCHEMBL24131326 | 0.74 | RAB9A (0.48) | RAB9AHSD11B1JAK2JAK1HRH3 | |
| SCHEMBL14243062 | 0.73 | CHRNB2 (0.54) | TSHRRAB9ASMN1; SMN2HSD11B1KIT | |
| SCHEMBL24711925 | 0.72 | TSHR (0.58) | TSHRSMN1; SMN2HRH3CYP2D6 | |
| SCHEMBL24131317 | 0.72 | RAB9A (0.52) | RAB9ASMN1; SMN2JAK2JAK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |