Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055567 | 0.89 | TSHR (0.35) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL3711344 | 0.78 | CYP2C19 (0.38) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL21110596 | 0.75 | ADRA1A (0.36) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL4223239 | 0.75 | SMN1; SMN2 (0.46) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL1935273 | 0.72 | ALDH1A1 (0.39) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL4040747 | 0.72 | LMNA (0.46) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL6633999 | 0.71 | MAPT (0.48) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4229696 | 0.71 | CYP2D6 (0.39) | KDM4EKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL1760354 | 0.70 | — | — | |
| SCHEMBL2438348 | 0.70 | CYP2D6 (0.36) | KDM4CECE1CYP2D6CYP2C19ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093931-A2 | NOVEL PRODRUGS OF PHENOLIC DRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2013-06-27 | — | — | WO | claimed |