Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2342516 | 0.81 | MAOB (0.50) | CA2CA1TRPA1MEN1KMT2A | |
| SCHEMBL12136378 | 0.81 | MAOB (0.50) | CA2CA1TRPA1MEN1KMT2A | |
| SCHEMBL18947039 | 0.81 | MAOB (0.50) | CA2CA1TRPA1MEN1KMT2A | |
| SCHEMBL7590594 | 0.77 | PTGS2 (0.44) | MEN1KMT2ATSHRLMNA | |
| SCHEMBL5020596 | 0.76 | MAOB (0.62) | CA2CA1SRD5A2NR4A1NR4A2 | |
| SCHEMBL9506114 | 0.76 | MAOB (0.62) | CA2CA1SRD5A2NR4A1NR4A2 | |
| SCHEMBL28393877 | 0.74 | KMT2A (0.52) | CA2CA1SRD5A2NR4A1MEN1 | |
| SCHEMBL21113692 | 0.73 | MAOB (0.48) | MEN1KMT2ALMNA | |
| Aniline SCHEMBL7799247 | 0.73 | TSHR (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL11027747 | 0.73 | CA2 (1.00) | CA2CA1TRPA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |