Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | AOC2 | O75106 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | FHIT | P49789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505859 | 0.77 | BCHE (0.39) | ALDH1A1MAPTCYP3A4KDM4EKMT2A | |
| SCHEMBL620180 | 0.76 | TSHR (0.37) | MAPTPSMB1TSHRPSMB5L3MBTL1 | |
| SCHEMBL8698153 | 0.76 | TSHR (0.37) | MAPTPSMB1TSHRPSMB5L3MBTL1 | |
| SCHEMBL2703082 | 0.74 | MAPT (0.38) | ALDH1A1MAPTPSMB1TSHRL3MBTL1 | |
| SCHEMBL8723032 | 0.73 | BCHE (0.51) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27500883 | 0.72 | POLB (0.36) | ALDH1A1MAPTPSMB1TSHRPSMB5 | |
| SCHEMBL8677952 | 0.72 | NOTUM (0.48) | ALDH1A1GAAKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL23732646 | 0.71 | PSMB1 (0.36) | ALDH1A1MAPTPSMB1TSHRL3MBTL1 | |
| SCHEMBL558876 | 0.70 | ESR1 (0.34) | KDM4EPSMB1TSHR | |
| SCHEMBL6535697 | 0.69 | NOTUM (0.59) | MAPTCYP1A2CYP3A4GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |
| US-9617216-B2 | Antifungal oxodihydropyridinecarbohydrazide derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2017-04-11 | — | — | US | disclosed |
| US-9617216-B2 | Antifungal oxodihydropyridinecarbohydrazide derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2017-04-11 | — | — | US | disclosed |
| US-9617216-B2 | Antifungal oxodihydropyridinecarbohydrazide derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2017-04-11 | — | — | US | disclosed |
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-10-20 | — | — | US | disclosed |
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-10-20 | — | — | US | disclosed |
| EP-3060549-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2016-08-31 | — | — | EP | disclosed |
| EP-3060549-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2016-08-31 | — | — | EP | disclosed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | disclosed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | disclosed |
| WO-2015060613-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015060613-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | PITHD1, HPD, QDPR | ALDH1A1 773/4885AOC2 89/4885MAPT 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.