Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 5/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.35 |
| ▸ | BCR | P11274 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12833375 | 0.93 | KIF11 (0.39) | ESR1SMN1; SMN2NPC1TP53MAPK1 | |
| SCHEMBL8934991 | 0.93 | KIF11 (0.39) | ESR1SMN1; SMN2NPC1TP53MAPK1 | |
| SCHEMBL1505815 | 0.93 | KIF11 (0.39) | ESR1SMN1; SMN2NPC1TP53MAPK1 | |
| SCHEMBL4320790 | 0.88 | NPC1 (0.55) | ESR1SMN1; SMN2NPC1TP53MAPK1 | |
| SCHEMBL4530562 | 0.85 | RAB9A (0.35) | ESR1SMN1; SMN2RAB9AKIF11HSD17B10 | |
| SCHEMBL13422208 | 0.84 | KMT2A (0.43) | ESR1SMN1; SMN2NPC1RAB9AKIF11 | |
| SCHEMBL13422323 | 0.84 | ESR2 (0.50) | ESR1SMN1; SMN2NPC1TP53MAPK1 | |
| SCHEMBL28280786 | 0.83 | MAPK1 (0.39) | TP53MAPK1RAB9AKIF11HSD17B10 | |
| SCHEMBL16743474 | 0.83 | HSD17B10 (0.40) | SMN1; SMN2NPC1TP53MAPK1CASP3 | |
| SCHEMBL14205337 | 0.83 | HSD17B10 (0.40) | SMN1; SMN2NPC1TP53MAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897692-B2 | Sulfonated perfluorocyclobutane block copolymers and proton conductive polymer membranes | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897692-B2 | Sulfonated perfluorocyclobutane block copolymers and proton conductive polymer membranes | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897693-B2 | Proton conductive polymer electrolytes and fuel cells | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090278091-A1 | SULFONATED PERFLUOROCYCLOBUTANE BLOCK COPOLYMERS AND PROTON CONDUCTIVE POLYMER MEMBRANES | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090278091-A1 | SULFONATED PERFLUOROCYCLOBUTANE BLOCK COPOLYMERS AND PROTON CONDUCTIVE POLYMER MEMBRANES | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-20090281262-A1 | PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2009-11-12 | — | — | US | disclosed |