SCHEMBL4530562

SCHEMBL4530562

FC(F)=C(F)Oc1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.35
LMNA P02545 2/20 0.33
KMT2A Q03164 5/20 0.31
MEN1 O00255 3/20 0.31
HSD17B10 Q99714 2/20 0.31
HTT P42858 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
ELANE P08246 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
KIF11 P52732 1/20 0.30
POLB P06746 2/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12833374 0.92 KMT2A (0.43) RAB9AKMT2AMEN1ALDH1A1MAPT
SCHEMBL12833375 0.92 KIF11 (0.39) RAB9ALMNAKMT2AMEN1HSD17B10
SCHEMBL1505815 0.92 KIF11 (0.39) RAB9ALMNAKMT2AMEN1HSD17B10
SCHEMBL8934991 0.92 KIF11 (0.39) RAB9ALMNAKMT2AMEN1HSD17B10
SCHEMBL1505923 0.89 MEN1 (0.48) RAB9ALMNAKMT2AMEN1HSD17B10
SCHEMBL9167461 0.87 TDP1 (0.46) KMT2AMEN1HSD17B10ALDH1A1MAPT
SCHEMBL9169744 0.87 CA1 (0.52) RAB9ALMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL1505790 0.87 CYP2A6 (0.38) RAB9ALMNAKMT2AMEN1ALDH1A1
SCHEMBL9909122 0.87 LMNA (0.52) LMNAKMT2AMEN1ALDH1A1MAPT
SCHEMBL2330129 0.86 LTA4H (0.41) HSD17B10ALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7457508-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2008-11-25 US claimed
US-20070217755-A1 Polymeric compositions comprising quantum dots,optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2007-09-20 US claimed
US-5540997-A POLYMERS FOR ELECTROOPTICAL SWITCHES AND DISPLAY DEVIVES THE DOW CHEMICAL COMPANY (US) 1996-07-30 US claimed
US-7897693-B2 Proton conductive polymer electrolytes and fuel cells GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-03-01 US disclosed
US-20090281262-A1 PROTON CONDUCTIVE POLYMER ELECTROLYTES AND FUEL CELLS GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-11-12 US disclosed
US-7570864-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same ALCATEL-LUCENT USA INC. (US) 2009-08-04 US disclosed
US-20090034930-A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2009-02-05 US disclosed
US-7457508-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2008-11-25 US disclosed
US-20070217755-A1 Polymeric compositions comprising quantum dots,optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2007-09-20 US disclosed
US-7197226-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2007-03-27 US disclosed
US-20060208223-A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2006-09-21 US disclosed
US-7065285-B2 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same LUCENT TECHNOLOGIES INC. (US) 2006-06-20 US disclosed
US-20050117868-A1 Polymeric compositions comprising quantum dots, optical devices comprising these compositions and methods for preparing same BARINGS FINANCE LLC, AS COLLATERAL AGENT 2005-06-02 US disclosed
EP-1290041-B1 SULFONATED PERFLUOROCYCLOBUTANE ION-CONDUCTING MEMBRANES 3M INNOVATIVE PROPERTIES CO (US) 2004-05-19 EP disclosed
US-6559237-B1 Sulfonated aromatic perfluorocyclobutane polymers meeting a condition selected from: a) the equivalent weight of the polymer is 5000 or less, and b) the proton conductivity of the polymer at 25 degrees C. is 0.01 Siemens per centimeter (S/cm) 3M INNOVATIVE PROPERTIES COMPANY 2003-05-06 US disclosed
EP-1290041-A1 SULFONATED PERFLUOROCYCLOBUTANE ION-CONDUCTING MEMBRANES 3M Innovative Properties Company (US) 2003-03-12 EP disclosed
WO-2001094427-A1 SULFONATED PERFLUOROCYCLOBUTANE ION-CONDUCTING MEMBRANES 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-13 WO disclosed
US-5540997-A POLYMERS FOR ELECTROOPTICAL SWITCHES AND DISPLAY DEVIVES THE DOW CHEMICAL COMPANY (US) 1996-07-30 US disclosed