Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508311 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2TDP1GSK3B | |
| SCHEMBL1458166 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTSMN1; SMN2TDP1GSK3B | |
| SCHEMBL15209900 | 0.85 | LDHA (0.50) | ALDH1A1HTTSMN1; SMN2TDP1PSEN1 | |
| SCHEMBL25035714 | 0.77 | TSHR (0.57) | ALDH1A1HTTSMN1; SMN2TDP1GSK3B | |
| SCHEMBL29234164 | 0.76 | LPAR1 (0.48) | ALDH1A1HTTSMN1; SMN2TDP1GSK3B | |
| SCHEMBL27017044 | 0.76 | SMN1; SMN2 (0.41) | ALDH1A1HTTSMN1; SMN2TDP1PSEN1 | |
| SCHEMBL15215172 | 0.76 | ACHE (0.48) | ALDH1A1TDP1PSEN1PSEN2APH1B | |
| SCHEMBL20472138 | 0.75 | LDHA (0.45) | ALDH1A1HTTSMN1; SMN2TDP1PSEN1 | |
| SCHEMBL17271883 | 0.74 | HTT (0.47) | ALDH1A1HTTSMN1; SMN2TDP1LDHA | |
| SCHEMBL17605407 | 0.74 | JAK1 (0.41) | TDP1MEN1KMT2ATSHRYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |