Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15209900 | 0.81 | LDHA (0.50) | SMN1; SMN2APLNRPSEN1PSEN2APH1B | |
| SCHEMBL15058845 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2APLNRPSEN1PSEN2APH1B | |
| SCHEMBL1458166 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2APLNRPSEN1PSEN2APH1B | |
| SCHEMBL3508311 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2APLNRPSEN1PSEN2APH1B | |
| SCHEMBL17271883 | 0.75 | HTT (0.47) | SMN1; SMN2APLNRALDH1A1HTTSLC6A4 | |
| SCHEMBL15215172 | 0.71 | ACHE (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15898813 | 0.70 | PSEN1 (0.47) | SMN1; SMN2KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL28551807 | 0.70 | APLNR (0.40) | SMN1; SMN2APLNRALDH1A1HTTSLC6A4 | |
| SCHEMBL20472138 | 0.68 | LDHA (0.45) | SMN1; SMN2APLNRPSEN1PSEN2APH1B | |
| SCHEMBL25402687 | 0.67 | HTT (0.45) | SMN1; SMN2APLNRALDH1A1HTTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016152-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016152-A1 | ACTIVE COMPOUND COMBINATIONS | CYP51A1, ERG28, BROX | SMN1; SMN2 4195/4885KDM4E 978/4885CTBP2 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.