Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.48 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.48 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29658338 | 1.00 | TSHR (0.48) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL1005841 | 0.87 | TSHR (0.55) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL1996062 | 0.87 | ALDH1A1 (0.55) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| Hydrochloric Acid SCHEMBL28212666 | 0.85 | TSHR (0.53) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL15542221 | 0.85 | HTT (0.42) | TSHRALDH1A1HIF1ACYP19A1CA1 | |
| Hydrazine SCHEMBL28307217 | 0.83 | TSHR (0.52) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL20040867 | 0.83 | HTT (0.41) | TSHRALDH1A1HIF1ACYP19A1CA1 | |
| SCHEMBL13155130 | 0.82 | HTT (0.47) | TSHRALDH1A1TDP1HPGDHIF1A | |
| SCHEMBL1172437 | 0.80 | CYP19A1 (0.55) | TSHRALDH1A1CYP3A4TDP1HPGD | |
| SCHEMBL7203812 | 0.80 | CYP19A1 (0.62) | TSHRALDH1A1CYP3A4TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745739-A | Fluorine-based modified epoxy resin coating and preparation method thereof | 江西瀚泰新材料科技有限公司 | 2021-05-04 | — | — | CN | claimed |
| EP-4430042-B1 | 6-HETERO ARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| CN-120136750-A | Diamino thioether compound and application thereof in self-repairing polyimide optical film | 华中科技大学 | 2025-06-13 | — | — | CN | disclosed |
| EP-4267574-B1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20240254125-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. | 2024-08-01 | — | — | US | disclosed |
| US-12043632-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | AJAX THERAPEUTICS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| CN-115787350-B | Fluorine-containing deacidification liquid for paper | 国家图书馆 | 2024-05-31 | — | — | CN | disclosed |
| US-11970494-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | AJAX THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| US-11834454-B2 | Alkynylphenylbenzamide compounds and applications thereof | SHENZHEN NEWDEL BIOTECH CO., LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| EP-4267574-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2000072849-A1 | NOVEL EPIDERMAL GROWTH FACTOR RECEPTOR-BINDING COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2000-12-07 | — | — | WO | disclosed |
| US-6126917-A | RADIOLABELED COMPOUND | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2000-10-03 | — | — | US | disclosed |
| US-5675039-A | DIAMINES AS MONOMERS FOR POLYIMIDES HAVING DESIRABLE PROPERTIES | STULTS JEFFREY S (US) | 1997-10-07 | — | — | US | disclosed |
| US-5498691-A | FORMING POLYIMIDE RESINS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |
| EP-0413192-B1 | Method of making 1,1'-oxybis(3-nitro-5-Trifluoromethyl)benzene | OCCIDENTAL CHEM CO (US) | 1994-02-16 | — | — | EP | disclosed |
| EP-0413194-B1 | NOVEL BIS M-BENZOTRIFLUORIDE COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1993-06-16 | — | — | EP | disclosed |
| EP-0413192-A1 | Method of making 1,1'-oxybis(3-nitro-5-Trifluoromethyl)benzene | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413194-A1 | Novel bis m-benzotrifluoride compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-20 | — | — | EP | disclosed |
| US-4990670-A | Method of making 1,1'-oxybis (3-nitro-5-trifluoromethyl)-benzene | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970494-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | JAK2, JAK3, STAT5B | TSHR 1333/4885ALDH1A1 3735/4885CYP3A4 2677/4885 |
| US-11834454-B2 | Alkynylphenylbenzamide compounds and applications thereof | ALK, NTRK1, ERBB2 | TSHR 759/4885ALDH1A1 972/4885CYP3A4 1522/4885 |
| US-12043632-B2 | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors | JAK2, JAK3, STAT5B | TSHR 1333/4885ALDH1A1 3735/4885CYP3A4 2677/4885 |
| US-20240254125-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | JAK2, JAK3, STAT5B | TSHR 1333/4885ALDH1A1 3735/4885CYP3A4 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.