Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203812 | 0.94 | CYP19A1 (0.62) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| Fluoride SCHEMBL27574861 | 0.92 | CYP19A1 (0.59) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL30492205 | 0.84 | LMNA (0.47) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL1171962 | 0.84 | LMNA (0.47) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL2017968 | 0.84 | ALDH1A1 (0.50) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL2649497 | 0.84 | CYP19A1 (0.44) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL16960250 | 0.84 | CYP19A1 (0.44) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL8999906 | 0.84 | ALDH1A1 (0.50) | CYP19A1TSHRALDH1A1HIF1ALMNA | |
| SCHEMBL1944691 | 0.84 | ALDH1A1 (0.50) | CYP19A1TSHRALDH1A1MEN1HTT | |
| SCHEMBL3844920 | 0.84 | TSHR (0.71) | CYP19A1TSHRALDH1A1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504636-A | Preparation method of 2- (4-fluorophenyl) -6-nitro-4- (2, 2-trifluoroethoxy) -1, 2-benzothiazole-3-ketone and intermediate and application thereof | 上海筛杰生物医药有限公司 | 2025-02-25 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| JP-7017923-A | — | — | None | — | — | JP | disclosed |
| WO-2026090477-A1 | HELICASE INHIBITORS AND USES THEREOF | KIMIA THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-3985001-B1 | PHARMACEUTICAL COMPOSITION FOR USE IN TREATING A CANCER | SERVIER LAB (FR) | 2026-04-29 | — | — | EP | disclosed |
| US-12583815-B2 | Inhibitors of YAP/TAZ-TEAD oncoproteins, synthesis and use thereof | BRIDGENE BIOSCIENCES, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| CN-119504636-B | Preparation method of 2- (4-fluorophenyl) -6-nitro-4- (2, 2-trifluoroethoxy) -1, 2-benzothiazole-3-ketone and intermediate and application thereof | 上海筛杰生物医药有限公司 | 2026-03-13 | — | — | CN | disclosed |
| EP-4334298-B1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-12540129-B2 | KIF18A inhibitors | AMGEN INC. (US) | 2026-02-03 | — | — | US | disclosed |
| EP-4673137-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| US-20250382283-A1 | COMPOUNDS AND THEIR USES AS CD38 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO LTD (CN) | 2025-12-18 | — | — | US | disclosed |
| EP-0491968-A1 | Process for the preparation of N-alkyl-fluoroanilines | BAYER AG (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-4721790-A | Nucleophilic substitution process for fluoronitroaralkyloxazoline | ETHYL CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| EP-0150418-B1 | PROCESS FOR PREPARING FLUORINATED AROMATIC COMPOUNDS | BASF Aktiengesellschaft (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4568781-A | Preparation of fluorine-substituted aromatic compounds | BASF AKTIENGESELLSCHAFT (DE) | 1986-02-04 | — | — | US | disclosed |
| US-4540795-A | Fluoronitroaralkyloxazolines, derivatives thereof, and nucleophilic substitution processes for preparing them | ETHYL CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0150418-A1 | Process for preparing fluorinated aromatic compounds | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |
| US-4476337-A | Method for introducing fluorine into an aromatic ring | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1984-10-09 | — | — | US | disclosed |
| US-4423260-A | Method for introducing fluorine into an aromatic ring | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-12-27 | — | — | US | disclosed |
| US-4370278-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1983-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583815-B2 | Inhibitors of YAP/TAZ-TEAD oncoproteins, synthesis and use thereof | YAP1, TEAD1, TEAD2 | CYP19A1 4474/4885TSHR 1551/4885ALDH1A1 3155/4885 |
| US-12540129-B2 | KIF18A inhibitors | KIF18A, KIFC1, KIF2C | CYP19A1 1310/4885TSHR 2351/4885ALDH1A1 802/4885 |
| US-20250382283-A1 | COMPOUNDS AND THEIR USES AS CD38 INHIBITORS | CD38, FCGRT, CD22 | CYP19A1 2163/4885TSHR 3533/4885ALDH1A1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.