Sugi Predict

Sugi Predict / Compounds / SCHEMBL7203812

SCHEMBL7203812

SCHEMBL7203812

O=[N+]([O-])c1cc(F)cc([N+](=O)[O-])c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.62
▸ LMNA P02545 3/20 0.52
▸ TSHR P16473 2/20 0.52
▸ VCAM1 P19320 1/20 0.50
▸ CYP3A4 P08684 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ ALDH1A1 P00352 5/20 0.48
▸ HIF1A Q16665 2/20 0.46
▸ HSPB1 P04792 1/20 0.45
▸ MEN1 O00255 2/20 0.44
▸ HTT P42858 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ TDP1 Q9NUW8 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ PGR P06401 1/20 0.42
▸ POLB P06746 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ TTR P02766 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27574861 0.97 CYP19A1 (0.59) CYP19A1LMNATSHRVCAM1CYP3A4
SCHEMBL1172437 0.94 CYP19A1 (0.55) CYP19A1LMNATSHRVCAM1CYP3A4
SCHEMBL212845 0.85 CYP19A1 (0.81) CYP19A1LMNATSHRVCAM1CYP3A4
SCHEMBL30492205 0.84 LMNA (0.47) CYP19A1LMNATSHRVCAM1CYP3A4
SCHEMBL16960250 0.84 CYP19A1 (0.44) CYP19A1LMNATSHRVCAM1CYP3A4
SCHEMBL2649497 0.84 CYP19A1 (0.44) CYP19A1LMNATSHRCYP3A4ALDH1A1
SCHEMBL6645951 0.84 CYP19A1 (0.44) CYP19A1LMNATSHRVCAM1CYP3A4
SCHEMBL3844920 0.84 TSHR (0.71) CYP19A1LMNATSHRCYP3A4SMN1; SMN2
SCHEMBL8999906 0.84 ALDH1A1 (0.50) CYP19A1LMNATSHRALDH1A1HIF1A
SCHEMBL1171962 0.84 LMNA (0.47) CYP19A1LMNATSHRVCAM1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110713454-A Nitro-substituted indole compound and preparation method thereof 南京工业大学 2020-01-21 — — CN claimed
CN-110105220-A A method of m-phenylene diamine (MPD) is prepared using meta position oil as raw material 济南和润化工科技有限公司 2019-08-09 — — CN claimed
EP-4086242-B1 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE RIVUS PHARMACEUTICALS INC (US) 2026-04-08 — — EP disclosed
US-20250214944-A1 Novel Phenyl Derivatives Rivus Pharmaceuticals, Inc. 2025-07-03 — — US disclosed
CN-117024351-A Novel phenyl derivatives 里维斯制药股份有限公司 2023-11-10 — — CN disclosed
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2023-10-24 — — US disclosed
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2023-10-24 — — US disclosed
CN-110167918-B Novel Phenyl Derivatives 里维斯制药股份有限公司 2023-08-29 — — CN disclosed
CN-110713454-B Nitro-substituted indole compound and preparation method thereof 南京工业大学 2022-12-09 — — CN disclosed
EP-4086242-A1 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE Rivus Pharmaceuticals, Inc. (US) 2022-11-09 — — EP disclosed
US-20220135516-A1 Process of Fluorinating Inorganic Compounds by Direct Fluorination Fujian Yongjing Technology Co.,Ltd (CN) 2022-05-05 — — US disclosed
WO-2000056925-A2 METHODS FOR SINGLE NUCLEOTIDE POLYMORPHISM DETECTION ACLARA BIOSCIENCES, INC. (US) 2000-09-28 — — WO disclosed
US-5130457-A PROCESS FOR THE PREPARATION OF N,N-DISUBSTITUTED MONO- AND OLIGOURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1992-07-14 — — US disclosed
EP-0238925-B1 PROCESS FOR THE PREPARATION OF N,N-DISUBSTITUTED MONO AND OLIGOURETHANES BAYER AG (DE) 1990-02-28 — — EP disclosed
US-4721790-A Nucleophilic substitution process for fluoronitroaralkyloxazoline ETHYL CORPORATION (US) 1988-01-26 — — US disclosed
EP-0238925-A2 Process for the preparation of N,N-disubstituted mono and oligourethanes BAYER AG (DE) 1987-09-30 — — EP disclosed
EP-0150418-B1 PROCESS FOR PREPARING FLUORINATED AROMATIC COMPOUNDS BASF Aktiengesellschaft (DE) 1987-03-04 — — EP disclosed
US-4568781-A Preparation of fluorine-substituted aromatic compounds BASF AKTIENGESELLSCHAFT (DE) 1986-02-04 — — US disclosed
US-4540795-A Fluoronitroaralkyloxazolines, derivatives thereof, and nucleophilic substitution processes for preparing them ETHYL CORPORATION (US) 1985-09-10 — — US disclosed
EP-0150418-A1 Process for preparing fluorinated aromatic compounds BASF Aktiengesellschaft (DE) 1985-08-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795138-B2 Process of fluorinating inorganic compounds by direct fluorination AFF2, CYP4F2, AFF1 CYP19A1 284/4885LMNA 4746/4885TSHR 3235/4885
US-20250214944-A1 Novel Phenyl Derivatives TFAM, GOT2, NDUFAB1 CYP19A1 2557/4885LMNA 3170/4885TSHR 4046/4885
US-20220135516-A1 Process of Fluorinating Inorganic Compounds by Direct Fluorination AFF2, CYP4F2, AFF1 CYP19A1 284/4885LMNA 4746/4885TSHR 3235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.