Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | UGCG | Q16739 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 7/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017121 | 0.84 | ALOX5AP (0.47) | SCN9AALOX5APFEN1UGCGDRD1 | |
| SCHEMBL9069797 | 0.81 | ALOX5AP (0.55) | SCN9AALOX5APFEN1UGCGDRD1 | |
| SCHEMBL15060598 | 0.81 | ALOX5AP (0.44) | SCN9AALOX5APFEN1UGCG | |
| SCHEMBL11673547 | 0.76 | NAAA (0.50) | HTR7PTPRC | |
| SCHEMBL26509879 | 0.75 | TP53 (0.41) | DRD1ADRB2HTR7PTPRCRXRA | |
| SCHEMBL7368168 | 0.75 | CNR2 (0.51) | AR | |
| SCHEMBL11021709 | 0.74 | ADRB2 (0.47) | ADRB2HTR7 | |
| SCHEMBL28288419 | 0.73 | MAPT (0.52) | SCN9AALOX5APFEN1PTPRC | |
| SCHEMBL5413155 | 0.73 | L3MBTL1 (0.55) | AR | |
| SCHEMBL11022152 | 0.73 | TP53 (0.54) | ALOX5APFEN1ADRB2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471024-B2 | Tetrahydrofuropyridones | MERCK SHARP & DOHME, CORP. (US) | 2013-06-25 | — | — | US | disclosed |