SCHEMBL150620

SCHEMBL150620

C=C(CCCCOc1cccc(C(C)(C)C)c1O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
KDM4E B2RXH2 5/20 0.46
GAA P10253 4/20 0.46
TDP1 Q9NUW8 2/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
CA2 P00918 1/20 0.40
ATM Q13315 1/20 0.40
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7898719 0.84 JAK2 (0.40) GAAMAPTLMNA
SCHEMBL1264523 0.77 CA2 (0.53) ALDH1A1KDM4EGAATDP1MAPK1
SCHEMBL10390139 0.77 TDP1 (0.43) ALDH1A1KDM4EGAATDP1MAPK1
SCHEMBL11029455 0.77 KDM4E (0.47) ALDH1A1KDM4EGAAMAPK1HTT
SCHEMBL15283971 0.76 GAA (0.53) KDM4EGAAATMMAPTLMNA
SCHEMBL18544229 0.76 LMNA (0.43) ALDH1A1KDM4EGAATDP1MAPK1
SCHEMBL150621 0.76 ALDH1A1 (0.45) ALDH1A1KDM4EGAATDP1MAPK1
SCHEMBL7644940 0.72 KCNA3 (0.57) ALDH1A1KDM4ETDP1ATMKMT2A
SCHEMBL4836971 0.72 GAA (0.55) ALDH1A1KDM4EGAAATMMAPT
SCHEMBL19458668 0.71 KDM4E (0.60) ALDH1A1KDM4EGAAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9581728-B2 Retardation film, polarizing plate and liquid crystal display Konica Minolta, Inc. (JP) 2017-02-28 US disclosed
US-20150323703-A1 RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-11-12 US disclosed
US-20150049380-A1 POLARIZED FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2015-02-19 US disclosed
US-8824047-B2 Polarizing plate, optical film and image display NITTO DENKO CORPORATION (JP) 2014-09-02 US disclosed
US-8767295-B2 Polarizing plate manufacturing method NITTO DENKO CORPORATION (JP) 2014-07-01 US disclosed
US-20130330547-A1 ACTIVATING TREATMENT METHOD FOR OPTICAL FILM, METHOD FOR PRODUCING OPTICAL LAMINATED-FILM, OPTICAL LAMINATED-FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2013-12-12 US disclosed
US-8331025-B2 Polarizing plate, manufacturing method thereof, optical film and image display NITTO DENKO CORPORATION (JP) 2012-12-11 US disclosed
US-8184370-B2 Polarizing plate, manufacturing method therefor, optical film and image display NITTO DENKO CORPORATION (JP) 2012-05-22 US disclosed
US-20120057230-A1 POLARIZING PLATE MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
US-20100232018-A1 POLARIZING PLATE, MANUFACTURING METHOD THEREOF, OPTICAL FILM AND IMAGE DISPLAY NITTO DENKO CORPORATION (JP) 2010-09-16 US disclosed
US-20100220392-A1 POLARIZING PLATE, OPTICAL FILM AND IMAGE DISPLAY NITTO DENKO CORPORATION (JP) 2010-09-02 US disclosed
US-20090185271-A1 POLARIZING PLATE, MANUFACTURING METHOD THEREFOR, OPTICAL FILM AND IMAGE DISPLAY NITTO DENKO CORPORATION (JP) 2009-07-23 US disclosed