Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052542 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL13052521 | 0.79 | POLB (0.44) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL19749255 | 0.78 | POLB (0.32) | ALDH1A1POLBMAPTHPGD | |
| SCHEMBL19750675 | 0.77 | POLB (0.32) | POLB | |
| SCHEMBL19749263 | 0.72 | OPRM1 (0.32) | — | |
| SCHEMBL168807 | 0.71 | RAB9A (0.57) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL13388979 | 0.71 | RAB9A (0.57) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL13052506 | 0.69 | MEN1 (0.42) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL18034211 | 0.69 | KDM4E (0.31) | ALDH1A1KDM4EMEN1NPC1POLB | |
| SCHEMBL15198322 | 0.68 | KDM4E (0.39) | ALDH1A1KDM4EMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607431-B1 | Cyanine dye compounds | LIFE TECHNOLOGIES CORP (US) | 2016-08-24 | — | — | EP | disclosed |
| EP-2607431-A1 | Cyanine dye compounds | Life Technologies Corporation (US) | 2013-06-26 | — | — | EP | disclosed |