Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1506578 | 1.00 | ESR2 (0.59) | ESR2DRD2CYP3A4CYP2C9KCNH2 | |
| SCHEMBL1506422 | 1.00 | ESR2 (0.59) | ESR2DRD2CYP3A4CYP2C9KCNH2 | |
| SCHEMBL16742999 | 0.93 | ESR2 (0.64) | ESR2DRD2CYP3A4CYP2C9KCNH2 | |
| SCHEMBL11046077 | 0.90 | ESR2 (0.49) | ESR2DRD2CYP3A4CYP2C9KCNH2 | |
| SCHEMBL1515026 | 0.89 | DRD2 (0.59) | DRD2ALDH1A1KDM1ASMN1; SMN2MAPT | |
| SCHEMBL14716871 | 0.89 | DRD2 (0.53) | ESR2DRD2ALDH1A1KDM1ASMN1; SMN2 | |
| SCHEMBL2730373 | 0.89 | DRD2 (0.53) | ESR2DRD2ALDH1A1KDM1ASMN1; SMN2 | |
| SCHEMBL1095456 | 0.86 | APP (0.51) | ESR2DRD2CYP3A4CYP2C9KCNH2 | |
| SCHEMBL1095457 | 0.86 | APP (0.51) | ESR2DRD2CYP3A4CYP2C9KCNH2 | |
| Bicarbonate SCHEMBL6207408 | 0.84 | ALDH1A1 (0.52) | DRD2ALDH1A1KDM1ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106999450-B | Immunomodulator | 弗莱塞斯生物科学公司 | 2021-07-09 | — | — | CN | disclosed |
| EP-3215142-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10206893-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180325889-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2018-11-15 | — | — | US | disclosed |
| EP-3215142-A2 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| CN-106999450-A | immunomodulator | 弗莱塞斯生物科学公司 | 2017-08-01 | — | — | CN | disclosed |
| US-20170143649-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-05-25 | — | — | US | disclosed |
| US-9598422-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| WO-2016114066-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2016-07-21 | — | — | WO | disclosed |
| WO-2016114346-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2016-07-21 | — | — | WO | disclosed |
| WO-2007081569-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-1998031697-A1 | ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF | SANKYO COMPANY, LIMITED (JP) | 1998-07-23 | — | — | WO | disclosed |
| EP-0303398-B1 | PREPARATION PROCESS OF 4-(4-HYDROXYPHENYL)-CYCLOHEXANOL | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0303398-A1 | Preparation process of 4-(4-hydroxyphenyl)-cyclohexanol | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-02-15 | — | — | EP | disclosed |
| US-4631328-A | LIQUID CRYSTALS | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |
| EP-0090282-B1 | POLYMERS HAVING MESOGEN GROUPS AND COLOURING MATTER IN THE SIDE CHAIN | BASF Aktiengesellschaft (DE) | 1986-02-05 | — | — | EP | disclosed |
| EP-0035902-B1 | 1-(4-ARYL-CYCLOHEXYL)PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-31 | — | — | EP | disclosed |
| EP-0090282-A1 | Polymers having mesogen groups and colouring matter in the side chain | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |
| US-4329353-A | ANTIEMETIC AND NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-05-11 | — | — | US | disclosed |
| EP-0035902-A1 | 1-(4-Aryl-cyclohexyl)piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206893-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | ESR2 1493/4885DRD2 2086/4885CYP3A4 1482/4885 |
| US-20170143649-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | ESR2 1493/4885DRD2 2086/4885CYP3A4 1482/4885 |
| US-20180325889-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | ESR2 1493/4885DRD2 2086/4885CYP3A4 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.