Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650918 | 0.82 | HTR2A (0.59) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| SCHEMBL5464795 | 0.76 | PIM1 (0.59) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| SCHEMBL10613637 | 0.68 | PTGS1 (0.53) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| SCHEMBL15064785 | 0.66 | HTR2A (0.56) | HTR2ADRD2SLC6A4HRH1CHRM2 | |
| SCHEMBL5323524 | 0.66 | CES1 (0.53) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| SCHEMBL7985761 | 0.66 | HTR1A (0.54) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| SCHEMBL8199134 | 0.65 | SLC6A2 (0.63) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| Depramine SCHEMBL29489714 | 0.65 | HTR1A (0.73) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| Depramine SCHEMBL2108027 | 0.65 | HTR1A (0.73) | HTR2AHTR1ADRD2SLC6A4HRH1 | |
| SCHEMBL8402837 | 0.65 | MTNR1A (0.54) | HTR2AHTR1ADRD2SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130174289-A1 | Na+/Mg2+ Exchanger | FBN - LEIBNITZ-INSTITUT FUR NUTZTIERBIOLOGIE (DE) | 2013-07-04 | — | — | US | disclosed |