Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401234 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL906300 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL1305795 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Lithium Ion SCHEMBL1458084 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Silver SCHEMBL219594 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL20162191 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Potassium Ion SCHEMBL1305480 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Tetramethylammonium Ion SCHEMBL593540 | 0.93 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL6342389 | 0.93 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL447369 | 0.84 | HSD11B1 (0.31) | ALDH1A1SMN1; SMN2HSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9527959-B2 | Moisture curable organopolysiloxane composition | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527959-B2 | Moisture curable organopolysiloxane composition | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-20150005443-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-01 | — | — | US | disclosed |
| US-20150005443-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-01-01 | — | — | US | disclosed |
| EP-2797692-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | Momentive Performance Materials Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| EP-2797692-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | Momentive Performance Materials Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| CN-104136118-A | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MAT INC | 2014-11-05 | — | — | CN | disclosed |
| WO-2013101755-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013101755-A1 | MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |