Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401234 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL15065488 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL1305795 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Lithium Ion SCHEMBL1458084 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL20162191 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Potassium Ion SCHEMBL1305480 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL906300 | 0.97 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| Tetramethylammonium Ion SCHEMBL593540 | 0.93 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL6342389 | 0.93 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2HSD17B10MEN1LMNA | |
| SCHEMBL447369 | 0.84 | HSD11B1 (0.31) | ALDH1A1SMN1; SMN2HSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116200187-A | Ionic metallic iridium complex and preparation method and application thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | claimed |
| US-11880134-B2 | Salts and photoresists comprising same | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2024-01-23 | — | — | US | disclosed |
| CN-116283739-A | Ionic metal ruthenium complex, preparation method and application thereof | 中国科学院化学研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-116200187-A | Ionic metallic iridium complex and preparation method and application thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-115079517-A | Salt and photoresist comprising the same | 罗门哈斯电子材料有限责任公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-107001828-B | Radiation curable compositions | 爱克发有限公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20190227433-A1 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME | ROHM & HAAS ELECT MAT (US) | 2019-07-25 | — | — | US | disclosed |
| US-20190163058-A1 | SALTS AND PHOTORESISTS COMPRISING SAME | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2019-05-30 | — | — | US | disclosed |
| US-10248020-B2 | Acid generators and photoresists comprising same | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2019-04-02 | — | — | US | disclosed |
| US-20140186767-A1 | ACID GENERATORS AND PHOTORESISTS COMPRISING SAME | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2014-07-03 | — | — | US | disclosed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2212273-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009053832-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2009-04-30 | — | — | WO | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1167349-B1 | Chemical amplifying type positive resist composition | SUMITOMO CHEMICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6548220-B2 | Containing acid generator | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20020015913-A1 | Chemical amplifying type positive resist composition and sulfonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-07 | — | — | US | disclosed |
| EP-1167349-A1 | Chemical amplifying type positive resist composition and sulfonium salt | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | ALDH1A1 3154/4885SMN1; SMN2 579/4885HSD17B10 4444/4885 |
| US-20190163058-A1 | SALTS AND PHOTORESISTS COMPRISING SAME | SLC6A6, TST, SLC6A12 | ALDH1A1 3514/4885SMN1; SMN2 4651/4885HSD17B10 3548/4885 |
| US-11880134-B2 | Salts and photoresists comprising same | SLC6A6, TST, XPOT | ALDH1A1 3636/4885SMN1; SMN2 4676/4885HSD17B10 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.