Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.43 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253550 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL16054198 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2CYP1A2ALDH1A1LMNATSHR | |
| SCHEMBL15066406 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2CYP1A2ALDH1A1LMNATSHR | |
| SCHEMBL15066569 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2CYP1A2ALDH1A1LMNATSHR | |
| SCHEMBL16055929 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2NPSR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16951865 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL13104870 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL1547373 | 0.72 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL40188 | 0.72 | ALDH1A1 (0.65) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL16951940 | 0.72 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968212-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-01-20 | — | — | EP | claimed |
| EP-2797878-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE | Bio-Pharm Solutions Co., Ltd. (KR) | 2014-11-05 | — | — | EP | claimed |
| EP-2797879-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN ALLEVIATING OR TREATING PAIN AND NEUROPATHIC PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2014-11-05 | — | — | EP | claimed |
| EP-2797877-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS | Bio-Pharm Solutions Co., Ltd. (KR) | 2014-11-05 | — | — | EP | claimed |
| WO-2014142520-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | claimed |
| WO-2013100569-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MULTIPLE SCLEROSIS | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2013-07-04 | — | — | WO | claimed |
| WO-2013100567-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN ALLEVIATING OR TREATING PAIN AND NEUROPATHIC PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2013-07-04 | — | — | WO | claimed |
| WO-2013100568-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2013-07-04 | — | — | WO | claimed |
| EP-2968212-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-01-20 | — | — | EP | disclosed |
| EP-2797876-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS | Bio-Pharm Solutions Co., Ltd. (KR) | 2014-11-05 | — | — | EP | disclosed |
| WO-2014142520-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |
| WO-2013100571-A9 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2014-09-18 | — | — | WO | disclosed |
| WO-2013100571-A1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ALS | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2013-07-04 | — | — | WO | disclosed |