Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957483 | 0.84 | SMN1; SMN2 (0.33) | SMN1; SMN2DRD2DRD3ALDH1A1TSHR | |
| SCHEMBL16951342 | 0.83 | DRD2 (0.43) | SMN1; SMN2DRD2DRD3L3MBTL1PPP1R15A | |
| SCHEMBL16960825 | 0.78 | L3MBTL1 (0.39) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL5584500 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2DRD2DRD3L3MBTL1PPP1R15A | |
| SCHEMBL253550 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2DRD2DRD3L3MBTL1PPP1R15A | |
| SCHEMBL15066091 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2DRD2DRD3L3MBTL1PPP1R15A | |
| SCHEMBL9317682 | 0.75 | PPP1R15A (0.46) | SMN1; SMN2L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL16960605 | 0.73 | TRPA1 (0.38) | CYP1A2CYP3A4CYP2D6NFKB1ALDH1A1 | |
| SCHEMBL8379850 | 0.72 | LMNA (0.41) | SMN1; SMN2DRD2DRD3L3MBTL1PPP1R15A | |
| SCHEMBL16954692 | 0.71 | TP53 (0.39) | CYP1A2CYP3A4CYP2D6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |