Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454406 | 0.81 | GABRA1 (0.41) | ALDH1A1CYP3A4ALOX15TDP1MAPT | |
| SCHEMBL31290769 | 0.81 | GABRA1 (0.41) | ALDH1A1CYP3A4ALOX15TDP1MAPT | |
| SCHEMBL4647358 | 0.80 | CYP3A4 (0.46) | PTGDRPTGDR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL15066541 | 0.79 | PTGDR (0.50) | PTGDRPTGDR2ALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL6307100 | 0.79 | GABRA1 (0.39) | ALDH1A1CYP3A4ALOX15TDP1MAPT | |
| SCHEMBL5338575 | 0.79 | GABRA1 (0.59) | ALDH1A1CYP3A4TSHRALOX15TDP1 | |
| SCHEMBL1768780 | 0.78 | XDH (0.48) | ALDH1A1CYP3A4TSHRALOX15SMN1; SMN2 | |
| SCHEMBL15322058 | 0.77 | CYP3A4 (0.43) | ALDH1A1CYP3A4TSHRALOX15SMN1; SMN2 | |
| SCHEMBL775187 | 0.77 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRALOX15SMN1; SMN2 | |
| SCHEMBL671144 | 0.77 | PTGDR (0.40) | PTGDRPTGDR2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055287-B1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | LU QING BIN (CA) | 2019-11-06 | — | — | EP | disclosed |