Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302540 | 0.73 | TSHR (0.41) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL15302293 | 0.72 | HPGD (0.39) | CYP1A2KMT2ACYP2D6 | |
| SCHEMBL15301886 | 0.70 | HTR1B (0.43) | CNR1CNR2SLC6A4CYP1A2CYP2D6 | |
| SCHEMBL1262275 | 0.70 | CYP1A2 (0.54) | MAPK1MC5RCNR1CNR2SLC6A2 | |
| SCHEMBL9035787 | 0.70 | CASR (0.48) | MAPK1MC5RCNR1CNR2HTR2A | |
| SCHEMBL433146 | 0.69 | CYP1A2 (0.58) | MAPK1CNR1CNR2SLC6A2SLC6A4 | |
| SCHEMBL29400404 | 0.69 | CNR1 (0.56) | MAPK1MC5RCNR1CNR2SLC6A2 | |
| SCHEMBL4570584 | 0.69 | RAB9A (0.54) | CNR1CNR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15891047 | 0.68 | HTR1B (0.47) | CNR1CNR2BCHE | |
| SCHEMBL15302388 | 0.67 | KDM4E (0.40) | CYP1A2KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260458-B2 | Method of producing an organic silicon compound | DOW CORNING CORPORATION (US) | 2016-02-16 | — | — | US | disclosed |
| US-20150141689-A1 | Method Of Producing An Organic Silicon Compound | DOW TORAY CO., LTD. (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2797855-A1 | METHOD OF PRODUCING AN ORGANIC SILICON COMPOUND | Dow Corning Toray Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013100166-A1 | METHOD OF PRODUCING AN ORGANIC SILICON COMPOUND | DOW CORNING TORAY CO., LTD. (JP) | 2013-07-04 | — | — | WO | disclosed |