Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154827 | 0.98 | SIGMAR1 (0.40) | SIGMAR1NOS3NOS1NOS2TSHR | |
| SCHEMBL856889 | 0.95 | — | — | |
| SCHEMBL5858264 | 0.86 | — | — | |
| SCHEMBL7486263 | 0.71 | — | — | |
| SCHEMBL21591581 | 0.71 | CHRNB2 (0.41) | — | |
| SCHEMBL7486383 | 0.71 | — | — | |
| SCHEMBL3272855 | 0.71 | TNKS2 (0.32) | — | |
| SCHEMBL21591599 | 0.71 | PNMT (0.41) | — | |
| SCHEMBL2119378 | 0.67 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL2122945 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4739 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344342-A | Substituted polyaromatic ring derivatives, compositions and uses thereof | 康迈迪森(北京)医药科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118324816-A | Organometallic compound, light-emitting device, electronic apparatus, and electronic device | 三星显示有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-117917420-A | Organometallic compound, light-emitting device, electronic apparatus, and electronic device | 三星显示有限公司 | 2024-04-23 | — | — | CN | claimed |
| EP-4353262-A1 | NOVEL COMPOUND HAVING INHIBITORY ACTIVITY AGAINST PENDRIN, AND PHARMACEUTICAL USES THEREOF | UIF (University Industry Foundation), Yonsei University (KR) | 2024-04-17 | — | — | EP | claimed |
| CN-117813306-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物研发有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117794577-A | Novel compound with inhibitory activity on Pan Telin and pharmaceutical application thereof | 延世大学校产学协力团 | 2024-03-29 | — | — | CN | claimed |
| CN-117529202-A | Organometallic compound, light-emitting device, electronic apparatus, and electronic device | 三星显示有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117285484-A | Benzothiadiazine 1, 1-dioxide compounds inhibiting HDAC6 enzyme, preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117247336-A | Hydroxamic acid compound capable of inhibiting HDAC6 as well as preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247358-A | Benzodiazepine compound with HDAC6 inhibition activity and preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-12-19 | — | — | CN | claimed |
| EP-0728130-A1 | PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-28 | — | — | EP | claimed |
| WO-1996020689-A2 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-11 | — | — | WO | claimed |
| US-5532355-A | IMMUNOSUPPRESSANTS FOR ORGAN TRANSPLANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-02 | — | — | US | claimed |
| US-5519031-A | TREATMENT OF RESTENOSIS, IMMUNOSUPPRESIVE AGENTS, ANTIINFLAMMATORY AGENTS, FUNGICIDES OR ANTITUMOR AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-21 | — | — | US | claimed |
| US-5516780-A | IMMUNOSUPPRESSIVE, ANTIINFLAMMATORY, ANTIFUNGAL AND ANTITUMOR AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-14 | — | — | US | claimed |
| US-5434260-A | Treating transplantation rejection in mammals | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-07-18 | — | — | US | claimed |
| WO-1995013267-A1 | PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS | THE UPJOHN COMPANY (US) | 1995-05-18 | — | — | WO | claimed |
| EP-0618889-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LIMITED (GB) | 1994-10-12 | — | — | EP | claimed |
| WO-1994021650-A1 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-29 | — | — | WO | claimed |
| WO-1994010118-A1 | TRI-SUBSTITUTED PHENYL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH LIMITED (GB) | 1994-05-11 | — | — | WO | claimed |