⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067 | 0.95 | SIGMAR1 (0.41) | — | |
| SCHEMBL154827 | 0.93 | SIGMAR1 (0.40) | — | |
| SCHEMBL5858264 | 0.86 | — | — | |
| SCHEMBL21591581 | 0.71 | CHRNB2 (0.41) | — | |
| SCHEMBL7486263 | 0.71 | — | — | |
| SCHEMBL3272855 | 0.71 | TNKS2 (0.32) | — | |
| SCHEMBL7486383 | 0.71 | — | — | |
| SCHEMBL21591599 | 0.71 | PNMT (0.41) | — | |
| SCHEMBL2119378 | 0.67 | SIGMAR1 (0.32) | — | |
| SCHEMBL2122945 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344342-A | Substituted polyaromatic ring derivatives, compositions and uses thereof | 康迈迪森(北京)医药科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | claimed |
| CN-118290446-A | Compound for inhibiting and degrading c-MYC and medical application thereof | 西藏海思科制药有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118271316-A | Cycloheptenyl-containing derivative, pharmaceutical composition and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118255780-A | Compound for inhibiting and degrading c-MYC and medical application thereof | 西藏海思科制药有限公司 | 2024-06-28 | — | — | CN | claimed |
| EP-4385985-A1 | HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-06-19 | — | — | EP | claimed |
| CN-118206558-A | Compound capable of inhibiting and degrading AuroraA, pharmaceutical composition and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-118146224-A | Nitrogen-containing tricyclic derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117897385-A | Compound for degrading Bcl-2 family proteins and application of compound in medicine | 西藏海思科制药有限公司 | 2024-04-16 | — | — | CN | claimed |
| EP-4332100-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-03-06 | — | — | EP | claimed |
| WO-2024012570-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 西藏海思科制药有限公司 | 2024-01-18 | — | — | WO | claimed |
| WO-2023208165-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2023-11-02 | — | — | WO | claimed |
| CN-116554147-A | Pyrazole derivative, composition and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116496318-A | Heterocyclic derivative, composition and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116375742-A | Azaaromatic ring derivative, composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| EP-2834238-B1 | DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS | PFIZER (US) | 2017-02-01 | — | — | EP | claimed |
| US-9296745-B2 | Diacylglycerol acyltransferase 2 inhibitors | PFIZER INC. (US) | 2016-03-29 | — | — | US | claimed |
| US-20150087585-A1 | DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS | PFIZER INC. (US) | 2015-03-26 | — | — | US | claimed |
| EP-2834238-A1 | DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS | Pfizer Inc. (US) | 2015-02-11 | — | — | EP | claimed |
| WO-2013150416-A1 | DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITORS | PFIZER INC. (US) | 2013-10-10 | — | — | WO | claimed |