Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067763 | 0.85 | HTR2A (0.37) | ATMHTR2AHTR2CHTR2BERN1 | |
| SCHEMBL15067149 | 0.72 | RXFP1 (0.52) | ALDH1A1 | |
| SCHEMBL30839665 | 0.69 | HRH3 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL21541905 | 0.69 | HRH3 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL11369904 | 0.69 | KDM4E (0.50) | TRIM24TYRTRIM33ALDH1A1ERN1 | |
| SCHEMBL4845712 | 0.68 | HTR7 (0.47) | ALDH1A1ERN1KDM4EMAOB | |
| SCHEMBL19153327 | 0.67 | ALDH1A1 (0.53) | TRIM24TYRTRIM33CTSAALDH1A1 | |
| SCHEMBL4392162 | 0.67 | ALDH1A1 (0.53) | TRIM24TYRTRIM33ALDH1A1ERN1 | |
| SCHEMBL18284498 | 0.67 | ALDH1A1 (0.53) | TRIM24TYRTRIM33ALDH1A1ERN1 | |
| SCHEMBL4729218 | 0.67 | CHRNB2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797889-A1 | NOVEL ARYLALKENE DERIVATIVES AND USE THEREOF AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | Centaurus Biopharma Co., Ltd. (CN) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097773-A1 | NOVEL ARYLALKENE DERIVATIVES AND USE THEREOF AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2013-07-04 | — | — | WO | disclosed |