Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2B | P41595 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849532 | 0.81 | HPGD (0.44) | HPGDTSHRMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL15067832 | 0.80 | ATM (0.38) | HPGDTSHRMAPK1HSD17B10HTR2C | |
| SCHEMBL15067031 | 0.80 | HTR2C (0.38) | HTR2CHTR2BADRB2HTR1ACHRM5 | |
| SCHEMBL15066329 | 0.80 | ALDH1A1 (0.40) | HPGDTSHRMAPK1HSD17B10MAPT | |
| SCHEMBL3644175 | 0.80 | MAPT (0.38) | HPGDTSHRMAPK1HSD17B10MAPT | |
| SCHEMBL28624043 | 0.79 | GABRA1 (0.37) | HPGDTSHRMAPK1HSD17B10HTR2B | |
| SCHEMBL7613662 | 0.77 | — | — | |
| SCHEMBL457783 | 0.77 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1 | |
| SCHEMBL921324 | 0.76 | HPGD (0.42) | HPGDTSHRMAPK1HSD17B10HTR2C | |
| SCHEMBL2921706 | 0.76 | KDM4E (0.33) | HPGDTSHRMAPK1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033139-B | Heteroaryl piperidine and heteroaryl based piperazine derivative as fungicide | 拜耳知识产权有限责任公司 | 2019-11-19 | — | — | CN | claimed |
| US-9975889-B2 | Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-05-22 | — | — | US | claimed |
| US-9914728-B2 | Heteroaryl piperidine and heteroaryl piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-13 | — | — | US | claimed |
| CN-107033139-A | It is used as the heteroaryl piperidine and heteroaryl based piperazine derivative of fungicide | 拜耳知识产权有限责任公司 | 2017-08-11 | — | — | CN | claimed |
| US-20170044153-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH | 2017-02-16 | — | — | US | claimed |
| US-20170044154-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | claimed |
| CN-113195502-A | Macrocyclic influenza endonuclease inhibitors | 詹森生物制药有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-107266382-B | Heteroarylpiperidine and piperazine derivatives as fungicides | 拜耳知识产权有限责任公司 | 2020-10-27 | — | — | CN | disclosed |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-2921484-B1 | OXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2921485-B1 | ISOXAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-19 | — | — | US | disclosed |
| EP-2921495-B1 | HETEROARYLPIPERIDINE AND HETEROARYLPIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| EP-2921481-A1 | 4-PIPERIDINE CARBOXYLIC ACID DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-22 | — | — | US | disclosed |
| EP-2797899-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2014-11-05 | — | — | EP | disclosed |
| CN-104011032-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2014-08-27 | — | — | CN | disclosed |
| US-20140005224-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-02 | — | — | US | disclosed |
| CN-103492379-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2014-01-01 | — | — | CN | disclosed |
| WO-2013098229-A2 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044154-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | HPGD 1872/4885TSHR 3091/4885MAPK1 2081/4885 |
| US-20170044153-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | HPGD 1872/4885TSHR 3091/4885MAPK1 2081/4885 |
| US-10426169-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | RB1, RBX1, RRP12 | HPGD 3001/4885TSHR 2139/4885MAPK1 700/4885 |
| US-20180103641-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | HPGD 3001/4885TSHR 2139/4885MAPK1 700/4885 |
| US-20140005224-A1 | HETEROARYL PIPERIDINE AND HETEROARYL PIPERAZINE DERIVATIVES AS FUNGICIDES | PRXL2A, CYP1A1, CAT | HPGD 1872/4885TSHR 3091/4885MAPK1 2081/4885 |
| US-20150024935-A1 | HETEROARYLPIPERIDINE AND PIPERAZINE DERIVATIVES AS FUNGICIDES | RB1, RBX1, RRP12 | HPGD 3059/4885TSHR 2366/4885MAPK1 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.