SCHEMBL1506785

SCHEMBL1506785

C=Cc1cc(C(=O)O)cc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
ALDH1A1 P00352 5/20 0.47
HPGD P15428 4/20 0.47
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 2/20 0.47
CYP1A2 P05177 1/20 0.47
GLA P06280 1/20 0.47
CYP2C19 P33261 1/20 0.47
PTPN1 P18031 1/20 0.45
NPC1 O15118 1/20 0.43
GAA P10253 1/20 0.43
RAB9A P51151 1/20 0.43
MAPT P10636 3/20 0.42
PKM P14618 2/20 0.42
EGFR P00533 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3267828 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL1506771 0.81 PTPN1 (0.60) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL890496 0.76 MEN1 (0.61) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL30363668 0.76 MEN1 (0.55) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL7554285 0.76 MEN1 (0.55) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL27829330 0.76 PTPN1 (0.45) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL7542003 0.75 PTPN1 (0.45) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL163552 0.74 MEN1 (0.53) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL29406969 0.74 PTPN1 (0.65) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL1506780 0.74 NQO2 (0.55) MEN1KMT2AALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822588-B2 Fluorine-containing polymer and anti-static agent wherein same is used CENTRAL GLASS COMPANY, LIMITED (JP) 2014-09-02 US disclosed
US-8513457-B2 Fluorine-containing compound, fluorine-containing polymer, negative-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2013-08-20 US disclosed
EP-2289954-B1 FLUORINE-CONTAINING POLYMER AND ANTI-STATIC AGENT WHEREIN SAME IS USED CENTRAL GLASS CO LTD (JP) 2013-01-16 EP disclosed
US-20120226070-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2012-09-06 US disclosed
US-8187787-B2 Fluorine-containing compound, fluorine-containing polymer, negative-type resist composition, and patterning process using same CENTRAL GLASS COMPANY, LIMITED (JP) 2012-05-29 US disclosed
US-20110065857-A1 Fluorine-Containing Polymer and Anti-Static Agent Wherein Same is Used CENTRAL GLASS COMPANY, LIMITED (JP) 2011-03-17 US disclosed
EP-2289954-A1 FLUORINE-CONTAINING POLYMER AND ANTI-STATIC AGENT WHEREIN SAME IS USED Central Glass Company, Limited (JP) 2011-03-02 EP disclosed
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2009-01-08 US disclosed
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226070-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same RTF1, FGFR2, FGFR1 MEN1 2055/4885KMT2A 193/4885ALDH1A1 3780/4885
US-20090011199-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer, Negative-Type Resist Composition, and Patterning Process Using Same FGFR2, RTF1, ADGRF1 MEN1 1618/4885KMT2A 166/4885ALDH1A1 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.